Necrotizing Enterocolitis
Watchlist
Retrieved
2021-01-23
Source
Trials
—
Genes
TLR4,
HBEGF,
NOS3,
ACADM,
SNAI3,
CRYL1,
PARK7,
AKR1A1,
SORD,
SOD2,
OAT,
LTF,
LGALS2,
HSPA9,
ENO1,
NOS2,
ALDH2,
EGF,
TNF,
TLR2,
IKBKG,
CD14,
TLR9,
IL18,
TLR1,
TLR6,
CD40,
CD40LG,
MUC2,
TLR7
TLR4,
HBEGF,
NOS3,
ACADM,
SNAI3,
CRYL1,
PARK7,
AKR1A1,
SORD,
SOD2,
OAT,
LTF,
LGALS2,
HSPA9,
ENO1,
NOS2,
ALDH2,
EGF,
TNF,
TLR2,
IKBKG,
CD14,
TLR9,
IL18,
TLR1,
TLR6,
CD40,
CD40LG,
MUC2,
TLR7,
TLR5,
TJP1,
IL10RB,
IL10,
PTAFR,
IL1B,
PARP1,
TUBB,
TLR3,
BANP,
ADCY4,
VEGFA,
MBL2,
IL6,
MIF,
HGF,
LGR5,
NDUFS7,
SIGIRR,
NOD2,
EPO,
DEFB4B,
MIR431,
VIP,
MIR1290,
CLDN2,
NR1I2,
ALB,
ARRB2,
CCR9,
DEFB103A,
IL22,
IL23A,
TOLLIP,
ATG16L1,
DEFB103B,
IL33,
IL23R,
CTNNB1,
SLC10A2,
ASL,
IL17A,
DEFB4A,
SLC25A10,
EGFR,
CRP,
FCGRT,
FCN1,
GLRX,
HMGB1,
FOXA1,
CRHR2,
IGF1,
IL4,
IL4R,
IL11,
IRF5,
THBD,
CRHR1,
CPS1,
SMAD7,
MAP3K5,
MMP3,
COX2,
ACTA1,
PPARG,
MAPK8,
PTGS2,
REN,
DEFA6,
CAV1,
TGFB2,
MTCO2P12
Registered!
A rare intestinal disease characterized by potentially life-threatening inflammatory bowel necrosis predominantly affecting preterm neonates. Patients may present with feeding intolerance, lethargy, temperature instability, abdominal distention, blood-stained stools, diarrhea, bilious vomiting, apnea, and signs of sepsis. Radiographic features include pneumatosis intestinalis, portal venous gas, presence of fixed, dilated intestinal loops, bowel wall edema, and (in case of bowel perforation) pneumoperitoneum.