Silicone Granuloma

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Retrieved
2021-01-18
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Silicone granulomas are a skin condition that occur as a reaction to liquid silicones, and are characterized by the formation of nodules.:46

Formation of a granuloma is a common tissue response to a range of foreign bodies. Silicone can be directly injected into tissue as part of a cosmetic procedure or it can leak from silicone implants. The formation and consequences of silicon-induced granulomas is not well described or understood. The extent of damage that they cause is controversial.

Localization

  • Lymph node: Granulomatous lymphadenitis
  • Skin: Granulomatous dermatitis
  • Penis
  • Breast: Granulomatous mastitis
  • Face: Granulomatous facial reaction

Effects

Silicone-induced granuloma can be associated with fever, calcitriol-mediated hypercalcemia, reactive amyloidosis.


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See also

  • Granuloma
  • Skin lesion