Silicone Granuloma

Silicone granulomas are a skin condition that occur as a reaction to liquid silicones, and are characterized by the formation of nodules.^:46

Formation of a granuloma is a common tissue response to a range of foreign bodies. Silicone can be directly injected into tissue as part of a cosmetic procedure or it can leak from silicone implants. The formation and consequences of silicon-induced granulomas is not well described or understood. The extent of damage that they cause is controversial.

Localization

• Lymph node: Granulomatous lymphadenitis
• Skin: Granulomatous dermatitis
• Penis
• Breast: Granulomatous mastitis
• Face: Granulomatous facial reaction

Effects

Silicone-induced granuloma can be associated with fever, calcitriol-mediated hypercalcemia, reactive amyloidosis.

Gallery

See also

• Granuloma
• Skin lesion