Inflammatory Pseudotumor
Watchlist
Retrieved
2021-01-18
Source
Trials
—
Genes
ALK,
RANBP2,
TPM3,
CLTC,
TPM4,
CARS1,
ACVRL1,
SLPI,
ROS1,
NTRK3,
TP53,
KIT,
SMUG1,
EML4,
MDM2,
TFG,
COIL,
IL1R1,
STAT6,
CD274,
BCOR,
WDR48,
IL6,
ACTB,
DES,
CDK4,
ETV6,
ATIC,
FN1,
HMGA2
ALK,
RANBP2,
TPM3,
CLTC,
TPM4,
CARS1,
ACVRL1,
SLPI,
ROS1,
NTRK3,
TP53,
KIT,
SMUG1,
EML4,
MDM2,
TFG,
COIL,
IL1R1,
STAT6,
CD274,
BCOR,
WDR48,
IL6,
ACTB,
DES,
CDK4,
ETV6,
ATIC,
FN1,
HMGA2,
STAM2,
USP6,
SQSTM1,
TP63,
CD34,
SLBP,
RBPMS,
YWHAE,
WT1,
VIM,
CDKN2A,
CMD1B,
TNFRSF8,
ZC3H7B,
SEC31A,
TNF,
BRAF,
AMACR,
CCND1,
AZU1,
HEBP1,
ANO1,
MIB1,
ATF1,
RTL1,
WG,
DUX4,
MTCO2P12,
TNS1,
NKX2-1,
HDLBP,
TIMP3,
HNRNPA1,
IGF1R,
IGFBP5,
EWSR1,
ESR1,
LAG3,
ERBB2,
MKI67,
COX2,
NAB2,
NHS,
NPM1,
NTRK1,
PDGFRA,
PIK3CA,
PTGS2,
DCTN1,
RET,
ACE,
CCL2,
SETMAR,
CCN2,
SMARCA1,
SMARCA4,
SMARCB1,
SMN1,
SMN2,
CR2,
TFE3,
H3P10
Drugs
—
Registered!
According to the WHO classification, three lesional patterns can be observed
- Inflammatory myofibroblastic tumour, that can be associated with an ALK gene rearrangement
- Plasmocytic pattern ("plasma cell granuloma"), that can be linked to IgG4-related disease
- Fibrous and hyalinizing pattern: Pulmonary hyalinizing granuloma