Turcot Syndrome With Polyposis

Watchlist

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Retrieved

2021-01-23

Source

Orphanet

Trials

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Genes

APC, MUTYH, FAP, NTHL1, PLA2G1B, PLA2G2A, PTGS2, YWHAZ, AFAP1, PLB1

Drugs

Celecoxib ( CELEBREX, ONSENAL ), Eflornithine, Eflornithine hydrochloride ( ORNIDYL )

Celecoxib ( CELEBREX, ONSENAL ), Eflornithine, Eflornithine hydrochloride ( ORNIDYL ), Eflornithine in combination with sulindac, Eicosapentaenoic acid, Valproic acid, sodium

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Turcot syndrome with polyposis or Turcot syndrome type 2 is a form of familial adematous polyposis, characterized by the concurrence of thousands of colonic adenomatous polyposis or colorectal cancer (CRC) and a primary central nervous system tumor (principally medulloblastoma). It is also associated with pigmented ocular fundus lesions.