Ovarian Tumor
Watchlist
Retrieved
2021-01-18
Source
Trials
—
Genes
CTNNB1,
BRCA2,
AKT1,
PTEN,
BRCA1,
KRAS,
PIK3CA,
ERBB2,
TP53,
MSH2,
MLH1,
OPCML,
CCNE1,
ESR1,
SMARCA4,
RAD51C,
BRAF,
RAD51D,
BRIP1,
EPCAM,
CDH1,
PRKN,
MSH6,
PMS2,
RNF43,
BABAM1,
CHMP4C,
RRAS2,
PMS1,
CXCL8
CTNNB1,
BRCA2,
AKT1,
PTEN,
BRCA1,
KRAS,
PIK3CA,
ERBB2,
TP53,
MSH2,
MLH1,
OPCML,
CCNE1,
ESR1,
SMARCA4,
RAD51C,
BRAF,
RAD51D,
BRIP1,
EPCAM,
CDH1,
PRKN,
MSH6,
PMS2,
RNF43,
BABAM1,
CHMP4C,
RRAS2,
PMS1,
CXCL8,
MUC16,
EGFR,
MSLN,
TIPARP,
MAPK1,
MTOR,
IL6,
MYC,
STAT3,
SKAP1,
FOLR1,
TUBB3,
FASN,
CDKN1B,
AKT2,
SPARC,
ZEB1,
TERT,
TNFSF10,
BIRC5,
YAP1,
MET,
STK11,
SULF1,
XIAP,
AREG,
WNT7A,
EDNRA,
TP63,
CYP1B1,
FGF1,
SKP2,
MAPK3,
MKI67,
SLC5A5,
GADD45A,
KLK10,
TYMS,
MAP2K1,
CAV1,
BNC2,
SOD2,
MECOM,
SLC2A1,
NME2,
BCL9,
CCND2,
ATP7B,
ATR,
ARL11,
ATG5,
SELENBP1,
ATG7,
NR5A1,
SPDEF,
DESI2,
HDAC6,
NECTIN2,
EREG,
DYRK1B,
RBL2,
TP53BP1,
ERCC4,
ANXA3,
HOXD1,
IL6ST,
CAMKK2,
BAP1,
TLR4,
SOD1,
JMJD6,
DLC1,
ALOX5,
URI1,
HOXB9,
POP4,
GRIK2,
CDK12,
GPR150,
WDR77,
C19orf12,
PLEKHF1,
SRSF10,
ALOX12B,
CCNH,
KANSL1,
SLC22A10,
ATF3,
HAUS6,
IL11RA,
PIK3R1,
LRRC59,
HOXD11,
PRC1,
ITGA8,
HOXD9,
PPP1CC,
AQP3,
LRRC46,
MACIR,
PRTFDC1,
DOK1,
ERCC6,
TRMT11,
APC,
CD82,
CHEK2,
RAD51,
XRCC2,
PALB2,
BARD1,
FERMT3,
SERPINC1,
HNF1B,
ATM,
FGFR2,
CHEK1,
NBN,
PVT1,
RELA,
DICER1,
WT1,
TGFBR2,
FANCM,
RAD51B,
RAD50,
HAGLR,
CDKN2B-AS1,
HOXD3,
LMNA,
KEAP1,
RSPO1,
UBE2F,
LAMA3,
IDH1,
HAGLROS,
ABRAXAS1,
MAP3K1,
WNT10A,
ATAD5,
SH2B3,
NME1,
IL10,
NEK10,
ESR2,
CNOT2,
JAKMIP2-AS1,
FSHR,
FLI1,
FOXO3,
EWSR1,
NOTCH3,
IGF2,
IGF1,
LINC00200,
NSF,
IDH2,
EZH2,
MIR145,
EGF,
ANKLE1,
PGR,
HRAS,
COL11A2,
ABCB1,
NCAM2,
GPX6,
KCNH1,
C11orf65,
GSTM1,
MMP2,
MMP9,
MIR214,
BOD1L1,
MDM2,
THSD7A,
EPHB2,
HNF1A-AS1,
ERBB3,
MRC1,
MRE11,
MIR4435-2HG,
JAZF1,
COX2,
CYTB,
HGF,
SLC9A9,
MTHFR,
TRNT,
MTX1,
MUC1,
ERCC1,
GBAP1,
MIR21,
ADAMTS16,
HIF1A,
HLA-B,
SH2D4B,
KRT8,
H3P10,
PIK3CB,
FBXO11,
PROM1,
PAK6,
NCLN,
CCND1,
BCL2,
ARID1A,
HMGA2,
MLLT10,
CXCR4,
UBE2F-SCLY,
PIK3CD,
WRN,
VEGFA,
VDR,
BUB1B,
TWIST1,
C11orf95,
TNF,
TGFB1,
CASP3,
SPP1,
ACOXL,
AR,
LINC00824,
MTCO2P12,
TTC28,
TBC1D9,
ZNF423,
DNM3,
RALY,
FAN1,
ADARB2,
MLH3,
PARP1,
BUB1B-PAK6,
SNCAIP,
LINC02652,
RASSF1,
CD274,
ALDH1A1,
MRPS18C,
WFDC2,
FRY,
PRANCR,
PLEKHM1,
FRAS1,
PTH,
TUBA1C,
PTK2,
ATXN2,
USHBP1,
CXCL12,
HOTAIR,
CDKN1A,
PTGS2,
CD44,
CMIP,
CDK2,
CD24,
PIK3CG,
KLK6,
CDKN2A,
CCL2,
GSTT1,
XRCC3,
MALAT1,
NFKB1,
NFE2L2,
FBXW7,
CLDN3,
AURKA,
FOXM1,
PPM1D,
EPHA2,
CYP1A1,
TP73,
SERPINE1,
ARHGAP24,
E2F1,
MIR200C,
IFNG,
KLK4,
IL17A,
GSTP1,
CEACAM5,
NCOA3,
DNMT1,
CTAG1B,
KDR,
MMP7,
PDCD1,
VTCN1,
TGM2,
MAP2K7,
GNRH1,
MTDH,
AMH,
ERCC2,
POU5F1,
GABPA,
DIRAS3,
HMGB1,
GAB2,
ABCG2,
CLDN4,
MIR205,
FLT1,
NACC1,
SIRT1,
ANXA2,
MIR34A,
CSF1,
MMP14,
LEP,
TEK,
MIR137,
BSG,
CYP19A1,
BMI1,
CXCR2,
SMAD4,
COL18A1,
POU5F1P4,
EMSY,
IGF1R,
MYD88,
SLPI,
MIR148A,
POU5F1P3,
SCN1A,
FILIP1L,
GSTK1,
TGFBI,
FANCF,
SLCO6A1,
NEAT1,
FN1,
GALT,
ANIB1,
PLAU,
SNAI1,
MMP3,
KLK5,
PLG,
GLI1,
ROR1,
ILK,
MIR182,
MIR200A,
IL1B,
HK2,
SLC12A9,
KLK7,
MIR139,
RSF1,
ITGB3,
WNT5A,
BRD2,
XRCC1,
NOTCH1,
RPS6KB1,
PPARG,
LPAR2,
NT5E,
HPSE,
CTAG1A,
PAEP,
APEX1,
CDKN2B,
CASP8,
BAX,
CXADR,
TIMM8A,
COMMD3-BMI1,
COMT,
MIR27A,
MIR146A,
CYP17A1,
EDN1,
IFI27,
SCGB2A1,
SOX2,
TWNK,
MIR429,
TIMP1,
AMHR2,
MCAM,
IL1A,
IL1RN,
KLRC4-KLRK1,
XPO1,
MIR152,
HSPB2,
HSPB1,
MIR203A,
CASR,
HLA-G,
UCA1,
OTUB1,
VCAN,
AXL,
PTGS1,
CRP,
ZEB2,
RAF1,
GRN,
NR1I3,
HBEGF,
ROR2,
IL24,
PAX2,
KLRK1,
PKM,
LGALS3,
HPGDS,
HSPB3,
KLK3,
BAG3,
ITGAV,
PAX8,
ITGB1,
LINC01194,
MIR125A,
PDCD4,
FOXP1,
VIM,
JAG1,
DNER,
ZNF217,
CLU,
MAP2K4,
PHB,
NEU1,
LOX,
LPA,
ETS1,
IL18,
MIR143,
IL4,
TICAM2,
IL1R1,
SST,
CDC42,
ACKR3,
CXADRP1,
IL2,
DCTN6,
ST8,
ST14,
CDK4,
MIR141,
BCL2L1,
SPA17,
SFRP1,
MAPK14,
CD34,
CBS,
CASP9,
DDB2,
ELAVL2,
KLK8,
EIF4E,
RNASET2,
KL,
DAB2,
MIR1307,
PCAT1,
RUNX3,
MMP1,
EEF1A2,
ISG15,
HTC2,
TYMP,
CYP2C8,
MEN1,
SPRY4-IT1,
CYP1A2,
HSPA5,
MIR506,
RAB25,
RBP1,
MCL1,
CTSL,
SPG7,
CTSB,
CCN1,
CCDC54,
ADIPOQ,
SOX9,
DNMT3A,
ADAM17,
SIRT3,
BRD4,
IL33,
ARR3,
TUSC3,
MIR30C2,
GATA6,
THY1,
MIR29B2,
PRKCA,
MIR29B1,
PAPPA,
TMED7,
CDX2,
MIR25,
SEMA4D,
H3P23,
PRKCI,
PRKAR1A,
CIB1,
BMP4,
MIR340,
BCL10,
F3,
FGF2,
MEG3,
TRIM13,
FGFR4,
CBSL,
ANGPT2,
IL21,
SMUG1,
COL11A1,
SCAF1,
MIR375,
KLF6,
PRKAA1,
GNRHR,
MNX1-AS1,
SQSTM1,
CDK7,
NEURL1,
GSK3B,
NR3C1,
PTAFR,
PSMD9,
MSC,
EPHX1,
ZNRD2,
PTCH1,
TMED7-TICAM2,
SPHK1,
GSTM2,
NRAS,
GDE1,
WWOX,
LGALS1,
ATP7A,
AIMP2,
PTPRC,
LTBP1,
S100B,
LHCGR,
CDK14,
CD47,
CHFR,
KHDRBS1,
NRP1,
PGF,
ABCC1,
CCL20,
CBLL2,
LGR6,
KLK1,
UGT1A1,
IGF2BP1,
CXCL11,
CGB5,
PMAIP1,
GAS5,
NFATC1,
NEK2,
UBR5,
APOE,
SERTAD1,
KRT19,
MARCHF7,
L1CAM,
PITX2,
TNFRSF10A,
NGF,
KIF14,
PPP2R1B,
S100A10,
CXCR6,
KLK11,
IL22,
MIR613,
CGA,
COX1,
RNASE3,
FST,
PAK1,
PPARGC1A,
AHR,
RB1,
PTBP1,
REST,
KLK14,
OGG1,
NTS,
MSH3,
CTCFL,
CREB1,
NTRK2,
PBX1,
DAXX,
SERPINF1,
SRA1,
PRKAA2,
PRKAB1,
PSAT1,
NTRK1,
HDAC9,
NOB1,
HEY,
SMAD7,
RAC1,
POSTN,
MIR532,
SLC31A1,
CCN2,
CKAP4,
PCNA,
MDK,
SETD2,
MDM4,
RPE65,
ARID3B,
MIR193B,
SNAI2,
LPAR1,
MIR142,
MIR223,
ABO,
HMGA1,
RBFOX2,
TCEAL7,
E2F2,
SNCG,
AQP5,
IGFBP2,
IGFBP3,
LPAR3,
IKBKB,
MIR199A2,
SMYD3,
MIR19A,
UTRN,
MIR497,
VEGFC,
MIAT,
MIR199A1,
MIR1271,
MUL1,
TMPRSS3,
SLIT2,
MIR363,
BCL3,
MIR15A,
MIR155,
HOXA10,
GPC3,
SP1,
HOXA9,
MIR30C1,
VCAM1,
MIR150,
HOXA7,
TIMP2,
CALCR,
STAT1,
MIR31,
UVRAG,
MIR193A,
ICAM1,
ASNS,
MIR17,
FGFR1,
LIN28A,
FGF7,
GDF15,
TSG101,
LIN28B,
MIR503,
ACTB,
BBC3,
SIK2,
MARCHF1,
POLE,
FAP,
ADM,
SRSF3,
ITGA5,
MIR335,
SHMT1,
SHBG,
DPH1,
MIR133B,
FAS,
THEMIS2,
ZFAS1,
WEE1,
FABP4,
HDAC1,
TUG1,
MTA1,
ABCA4,
VEGFD,
ENG,
INHA,
MIR206,
CXCR3,
DUSP1,
FHIT,
TRPC3,
MIR134,
GORASP1,
PDCD5,
CDR2,
TNFSF15,
PRSS8,
TFAP2A,
CDKN3,
PSMB9,
HTRA1,
NR1H2,
PSMB8,
FKBP14,
TGFA,
ARHGAP10,
TFAM,
PSEN2,
PSG2,
TFF1,
KLK15,
LOC100288966,
CALB2,
SCO2,
ABCB6,
QRSL1,
ARRB1,
STS,
ANXA6,
HDAC7,
IL23A,
GGCT,
LAPTM4B,
PPP2R1A,
UBE2N,
CLDN10,
DNM1L,
CHI3L1,
YWHAZ,
PPA1,
MBD2,
TTR,
CDCP1,
BMP7,
PON1,
DDR1,
SPAG9,
TOP2A,
TNFRSF1A,
PROS1,
PRL,
SCGB1A1,
THBS1,
THBS2,
GALNT14,
MAP2K6,
CGB3,
TIE1,
ABI1,
CEACAM3,
CEACAM7,
TIMP3,
TK1,
TKT,
TLR2,
CAMP,
FSD1,
HOTTIP,
TEAD1,
IL17D,
TRBV20OR9-2,
CDKN2D,
SLC22A3,
CD276,
PUM1,
TRPM7,
DDX4,
PPP1R2C,
S100A1,
SYTL2,
HDAC4,
RRM2,
PCLAF,
ADGRE5,
CBR1,
ING5,
ROS1,
ROCK1,
BRMS1L,
FSCN1,
WNT2B,
DOT1L,
DGCR8,
SLC16A1,
DDIT4,
AQP1,
CD40,
APOBEC3B,
TRIM56,
VTN,
CCL21,
NECTIN4,
CCL18,
HM13,
CCL5,
ENTPD1,
NPEPPS,
DLL4,
SIX1,
FSD1L,
MIR1182,
IKBKE,
FASLG,
SATB1,
CD59,
NR1I2,
ROCK2,
BRS3,
RGS10,
TRIM27,
SULT1E1,
BIRC2,
SSTR4,
DHDDS,
XBP1,
SPRY4,
STC1,
ATAD1,
PTPN11,
UBASH3B,
NANOG,
CDH13,
GGNBP2,
KLF4,
PTTG1,
TMSB10,
CAPNS1,
CDKN1C,
LSINCT5,
TCF21,
PTGDS,
CFLAR,
BIRC3,
MAK16,
RBM3,
GRAP2,
APOA1,
ASRGL1,
FAM83H-AS1,
REG1A,
RECQL,
RUNX1T1,
RBP4,
SOX11,
SOX18,
MIR708,
TLR9,
RUNX1,
KDM2B,
SPINK1,
SPINT1,
SOHLH2,
MELK,
MIR1236,
AFAP1-AS1,
CKB,
PIK3R3,
HTRA3,
HSPA4,
POLDIP2,
DAAM1,
HSD17B1,
HSD17B2,
HSF1,
HSPA1A,
HSPA9,
HPN,
HSP90AA1,
HSPD1,
MIR149,
TNC,
ID2,
KLK13,
HPR,
MIR489,
DLG2,
MIR191,
BCHE,
HLA-DRB1,
DENR,
KDM6B,
MIR195,
FOXA2,
MIR187,
MIR433,
CHD5,
HOXA4,
LOC111589215,
MIR18A,
HOXD@,
CHPT1,
PRPF31,
SERBP1,
IGF2R,
DNMT3B,
MIRLET7B,
MIRLET7A3,
PELP1,
ADRA1A,
SMURF1,
DOCK1,
JAK2,
IGFBP1,
JUN,
C12orf75,
ADRA2B,
KCNMA1,
CGB8,
KIT,
ISG20,
IRS1,
MIRLET7D,
MIRLET7E,
LTB4R2,
NID2,
ADH1B,
IDO1,
PNPLA2,
ADAM10,
MIR508,
ATN1,
IL7,
MIR498,
IL6R,
IL2RA,
IGFBP5,
MIR200B,
ACTN4,
EN2,
CUL4A,
FOSL2,
MIR96,
SRRM2,
MIR378A,
ESRRA,
MIR34C,
MIR381,
DOC2A,
GAB1,
BRMS1,
ERCC5,
GAS6,
RNF19A,
GATA4,
FOS,
FOLR2,
PADI4,
FLT4,
ETV4,
MUC13,
FOXO1,
F2R,
FOXC2,
DAPK2,
MIR373,
FGF8,
FGF3,
MIR328,
FCN2,
NUP62,
MIR370,
ERCC3,
MIR299,
EPAS1,
EPO,
GRB7,
PNO1,
CXCL1,
MIR211,
PDIA3,
GSN,
H3P9,
MIR28,
EIF5A2,
GTF2H1,
GUSB,
EPHA3,
SERPIND1,
SPARCL1,
WWTR1,
SNHG3,
GPR42,
SIK3,
TMEM158,
MIR22,
MIR221,
SFN,
SIRT5,
GNA12,
MIR23A,
ERBB4,
MIR23B,
MIR27B,
GJB1,
GJA1,
GHRH,
USP17L2,
DKK3,
CTCF,
CEACAM6,
CRMP1,
RCC2,
MRPL28,
PHF20,
NFKBIA,
MIR661,
AHSA1,
CTHRC1,
AGR3,
MYDGF,
NCK1,
ALCAM,
CSF2,
SPINT2,
PEA15,
MIR630,
NQO1,
IMMP1L,
USP39,
MIA,
BDNF,
ADAM19,
PLK2,
ZNF350,
TNFRSF12A,
CTNND1,
CYGB,
SEPTIN9,
HSPA14,
GSTO2,
MIR3064,
LYPD4,
CDR1-AS,
SERPINA5,
PCDH9,
ACVR1C,
AMBP,
TNFRSF10C,
ANGPT1,
CP,
PRDX1,
FOXP3,
PCSK6,
PEBP1,
VPS37A,
CLDN7,
NTSR1,
PDGFRA,
ING4,
CPOX,
ADAM12,
SNHG14,
NOTCH4,
PDK1,
DCTN4,
CRK,
ADGRE2,
AGR2,
AGPAT2,
MSMB,
CTSD,
MIR411,
LIMK1,
CMA1,
MCTS1,
KLK9,
ADRM1,
FZD7,
CYTOR,
CLIC1,
TGIF2,
LRP1,
MCAT,
RAB22A,
LMX1A,
CTNNBL1,
POTED,
BECN1,
LIF,
TAS2R64P,
KDM3A,
BTN3A2,
PBXIP1,
BAD,
LCP1,
RBMS3,
PTP4A3,
FSTL1,
CLCA1,
STC2,
TP73-AS1,
ATAD2,
TFPI2,
MAGEA3,
MIR551B,
MPO,
PYCARD,
NXT1,
EIF3A,
PGRMC1,
IL27,
CYP3A4,
LILRB1,
CYP27B1,
CCR7,
MIF,
SUB1,
MGMT,
KITLG,
SOCS1,
PRSS21,
MAP3K5,
SUSD2,
MIR572,
AGTR1,
PIN1,
PLAG1,
CD46,
HELQ,
STIP1,
H19,
TRAP1,
UBAP2,
RBM38,
NPLOC4,
ST6GALNAC1,
TEX11,
BEX4,
HIF1AN,
RNF20,
PARD3,
METTL3,
DIABLO,
BCCIP,
CNDP2,
NLRP2,
SLC39A4,
PCDHA1,
USE1,
ERVK-18,
PCDHB3,
NXF3,
BAIAP2L1,
TMPRSS4,
PRR11,
PBK,
ECHDC1,
ZNF415,
SOX6,
IL17RB,
MIR376C,
TRPV6,
BRD7,
BHLHE22,
TOX3,
ANGPTL3,
RPS6KA6,
TMEM97,
HTRA2,
TOR2A,
TMEM14A,
LINC00339,
DROSHA,
DNAJC15,
UPK3B,
ANKRD11,
CTAG2,
UHRF1,
SOCAR,
IRAIN,
CARD10,
SENP1,
ICOS,
PSMC3IP,
HOOK2,
LINC00312,
PRICKLE4,
EFEMP2,
ERVW-1,
BMP10,
TNFRSF21,
AGO2,
LAMP3,
QPCT,
BAMBI,
TNFAIP8,
PRDX5,
IFFO1,
H3P47,
CLIC4,
NECTIN3,
H3P13,
PNKD,
LINC02605,
CHMP2B,
TENM4,
FAM32A,
LOC110806263,
RAI14,
TES,
PHF19,
ERVK-32,
FBXO5,
EHF,
GBGT1,
GNL3,
LATS2,
CKAP2,
KCNIP3,
STOML2,
FALEC,
NSUN2,
EPB41L4A-DT,
APBB1IP,
EGLN1,
PAF1,
PCDHB17P,
MARCHF5,
XAF1,
TRIM44,
TRIT1,
VPS13C,
ESRP1,
CC2D1A,
NCK1-DT,
CHST11,
OCIAD1,
SSH3,
HCFC1R1,
CASC9,
USP47,
PANDAR,
TMEM45A,
ANO1,
WRAP53,
RIF1,
GOLPH3L,
RCBTB1,
ADAMTSL4,
UNC93A,
FGFRL1,
FXYD5,
DLEU1-AS1,
LINC00702,
ADIPOR1,
HSD17B12,
IGF2-AS,
TLR7,
TLR8,
SLC25A37,
DACT1,
CHST15,
ZMYND10,
UCHL5,
MIR6780B,
GULP1,
HSD17B7,
MIR8073,
TRIAP1,
VTA1,
SIRT6,
MIR6126,
LSR,
NLK,
RAB23,
UIMC1,
DARS-AS1,
GAL,
HMCN1,
RETN,
OTUD1,
PRSS55,
LINC00504,
MIR614,
MIR616,
MIR622,
RPL22L1,
TET3,
ABHD11-AS1,
MIR629,
DDX53,
STOML3,
MIR634,
MIR637,
PEBP4,
FEZF1-AS1,
SPINK13,
CNTN4,
MIR654,
MIR655,
MED19,
ZUP1,
MIR542,
OPN5,
SNORD89,
EWSAT1,
MIR4697HG,
LINC00515,
MIR552,
FDCSP,
ASPM,
TAB3,
MIR574,
NAALADL2,
LINC01342,
IPMK,
MIR590,
MIR591,
MIR595,
SPDYA,
LRWD1,
FOXK1,
MIR603,
ZNF385B,
COMMD1,
IL23R,
PHF13,
OSCAR,
MSI2,
ZC3H18,
ZG16B,
TARS3,
SPPL3,
H4-16,
LINC00161,
TWIST2,
NIBAN1,
FAM210B,
WDFY2,
CCR2,
SNORD114-10,
SNORD114-11,
MIR758,
MIR770,
CGB2,
CGB1,
NBAT1,
RBM45,
SNTN,
EIF5AL1,
CREB3L4,
SIX5,
PWAR1,
E2F7,
MIR663A,
CACUL1,
CASC8,
C10orf82,
ANXA8L1,
ZBED5-AS1,
MAGED4,
ZBTB46,
GATA5,
FOXR2,
OTUD6A,
BRD1,
TRIM50,
POTEF,
SLC13A5,
C20orf204,
AD10,
MIR217,
MIR215,
MIR423,
MIR424,
MIR212,
DUXAP9,
DUXAP10,
MIR208A,
CT45A1,
MIR204,
JPX,
MIR20A,
MIR19B1,
MIR448,
MIR196A2,
MIR186,
MIR183,
H4C15,
MIR18B,
MIR490,
MIR216A,
MIR383,
LINC00319,
MIR224,
MIR339,
MIR338,
XRCC6P5,
PALM2AKAP2,
MIR361,
POTEKP,
PIM3,
MIR17HG,
MIR99A,
MIR98,
MIR93,
MIR377,
MIR34B,
MIR382,
MIR320A,
MIR30D,
MIR30A,
MIR302A,
MIR301A,
MIR15B,
MIR146B,
MIR144,
MIR494,
NSUN4,
PRSS41,
GEN1,
PWAR4,
SOX2-OT,
MACC1,
ACTBL2,
GOLGA6A,
VSIG1,
STING1,
ANXA8,
CCDC144NL,
PRB2,
KRT6C,
TRIM59,
SCAI,
DLX6-AS1,
NME1-NME2,
SNHG20,
SCFV,
FLVCR1-DT,
POTEM,
MIR126,
MIR495,
MIR502,
MIR140,
MIR136,
MIR486-1,
MIR132,
MIR130B,
MIR130A,
MIR10A,
RPL10P17,
MIR107,
MIR106A,
MIR100,
MIRLET7C,
MIRLET7A2,
WDFY3-AS2,
LINC02145,
TEX19,
LARP4,
CDCA5,
GPR137,
LUCAT1,
APELA,
UBE2Z,
WNK1,
MARCKSL1,
DSCAM-AS1,
PCAT6,
DEPTOR,
NUCKS1,
HIF3A,
SOX17,
ARHGEF28,
PDLIM2,
ROBO3,
GIHCG,
ADAMTS9-AS2,
DPEP2,
VSIR,
MOAP1,
SNHG16,
DDA1,
CHAC1,
CAMKMT,
C9orf16,
VASH2,
HAND2-AS1,
MIR1908,
MICALL2,
MIR1290,
MIR1244-1,
VEPH1,
MIR718,
HECTD3,
MIR762,
RHBDF2,
MIR761,
MCPH1,
HMBOX1,
ADIPOR2,
SLC52A2,
BACE1-AS,
H3P41,
LINC01133,
LINC01210,
GOLPH3,
MICA,
CHP2,
INTS2,
MTA3,
HEG1,
TENM2,
BIRC6,
S100A14,
AICDA,
DANCR,
CEMIP,
SALL4,
PAK5,
CD248,
NUP107,
KMT5AP1,
CTNNBIP1,
PMEPA1,
NNT-AS1,
C1GALT1,
BDH2,
DNM3OS,
MTUS1,
MIB1,
PTBP2,
HEATR6,
SRR,
TMX2-CTNND1,
BACH2,
PBOV1,
CREBZF,
TMPOP2,
CXCL16,
HAMP,
ZNF398,
CIP2A,
KLHL1,
MIR4443,
TRMT9B,
USP36,
IFT80,
SEMA6A,
ERVK-20,
EHMT1,
AGBL2,
PRRT2,
NKD1,
H2BC12,
SNHG12,
MIR22HG,
NUDCD1,
HAVCR2,
MIR940,
TRIM52,
TXNDC17,
MIR942,
MIR543,
CBX2,
MYPN,
MIR760,
SPZ1,
SLX4,
L3MBTL3,
SYCE1L,
HSDL2,
TCHP,
KRT88P,
TSPYL5,
CSPP1,
NAV3,
EPSTI1,
FOXQ1,
NAPRT,
MIR298,
SPECC1,
VTRNA2-1,
MIR873,
TMEM88,
MIR374B,
MYLK3,
CABLES1,
UBXN11,
RSAD2,
RCCD1,
PYGO2,
MIR216B,
PLCZ1,
MIR934,
ABCC10,
KAT8,
ATRIP,
REG4,
AD12,
LIMD2,
TSGA10,
MIR1270,
TET1,
MIR1294,
PDGFD,
FER1L4,
TARS2,
MIR1181,
MUS81,
SPSB1,
NRSN2,
RMI1,
ESRP2,
GRHL2,
WLS,
MIR1180,
ZNF671,
NEK11,
MIR1207,
MIR1246,
SETD7,
SOX7,
NCALD,
SLC4A11,
IMMP2L,
HDAC10,
MIR346,
ITCH,
LINC00092,
JAM3,
LNCOC1,
MIR1284,
SHARPIN,
RNF146,
NUAK2,
VMP1,
MAP1LC3B,
FAM83D,
MAGED4B,
CLPTM1L,
ZNF318,
NAT2,
PLXNB2,
JAK1,
ITIH2,
ITGB8,
EIF6,
ITGB4,
ITGB2,
ITGAM,
ITGAE,
ITGA2,
IRF4,
IRF2,
ITGA6,
IRAK1,
INSR,
INSL3,
CXCL10,
INHBA,
ING1,
INCENP,
IMPA1,
TNFRSF9,
IL16,
IL15,
IL13RA2,
ITK,
JARID2,
GDNF,
JUNB,
LPP,
LNPEP,
LMX1B,
LIG4,
LGALS3BP,
LEPR,
LDHA,
LCN2,
LCK,
LCAT,
STMN1,
LAMC2,
KRT17,
KRT10,
KRT9,
KRT7,
KRT5,
KIFC1,
KISS1,
KIF2A,
KCNN3,
KCNH2,
JUND,
IL12A,
IL4R,
IFNA13,
IFNA1,
HLA-DMB,
NRG1,
HGFAC,
HDAC2,
HARS1,
H2AX,
GSTZ1,
GSTA2,
GRP,
CXCL2,
GRB2,
GPX3,
GPER1,
GPR4,
GPLD1,
GPI,
GPC1,
GNAI2,
GLI2,
GCLM,
GCLC,
GLB1,
GJB2,
HLA-DOA,
HLA-DQA1,
HLA-DRB3,
HP,
IDE,
ID4,
ID1,
HUS1,
HSPE1,
HSPA2,
HSPA1B,
HSD11B2,
HRC,
ERAS,
HOXC6,
HLA-E,
HOXA11,
HOXA5,
HOXA1,
HOXA@,
HNF4A,
FOXA1,
NR4A1,
HMOX1,
HMMR,
HMGB3,
LRPAP1,
LTF,
LUM,
NID1,
PDE4A,
PCYT1A,
PCNT,
PCM1,
PCDH8,
PAX1,
PAWR,
PAK3,
PAK2,
P4HB,
OVGP1,
CLDN11,
TNFRSF11B,
OPA1,
DDR2,
NTRK3,
SLC11A2,
PNP,
NOTCH2,
NOS3,
NOS2,
NQO2,
NME3,
PDGFB,
PDGFRB,
PDK4,
PLAGL1,
POLD1,
POLB,
PML,
PLXNB1,
PLK1,
PLEC,
PLCG1,
PLAUR,
PLAT,
PLAGL2,
PIP,
ENPP2,
PIM1,
SERPINB5,
PI3,
SLC25A3,
PGK1,
PFN2,
PFN1,
PF4,
PEG3,
PECAM1,
NM,
NGFR,
LY75,
NFKBIB,
MMP19,
MMP15,
MMP13,
MMP8,
MME,
CXCL9,
CD99,
MGAT3,
MEST,
MAP3K3,
MEF2D,
MEF2A,
MAPT,
MAP4,
MAN1A1,
MAGEA1,
MAFD2,
SMAD3,
SMAD2,
MARCKS,
NBR1,
TM4SF1,
TACSTD2,
MNAT1,
MPP2,
MSI1,
MYH6,
NFIL3,
NFE2,
NF2,
NEO1,
NEFH,
NEDD9,
NEDD8,
NDN,
NCAM1,
MYO6,
MYBL2,
MSN,
MYB,
MXI1,
MVD,
MUC4,
MUC2,
MTHFD1,
NUDT1,
MTF1,
MSX1,
MST1R,
GGT1,
GDI1,
POMC,
CD36,
CD14,
CD1A,
CCNG2,
CCNG1,
CCNB1,
KRIT1,
CCK,
CBR3,
SERPINA6,
CBFB,
RUNX2,
CAT,
CAPN2,
CAMK4,
CALR,
CALM3,
CALM2,
CALM1,
CALCA,
CALB1,
CACNB1,
CA9,
VPS51,
CD80,
CD63,
GDF2,
CD68,
MAP3K8,
COL5A1,
CNR1,
CNN1,
ABCC2,
LTB4R,
CCR4,
CCR1,
CLN3,
CHKA,
CHGB,
CHD2,
CEACAM8,
CEBPA,
CDR1,
CDK5,
CDH11,
CDH6,
CDC25B,
CDC25A,
CDC6,
CDK1,
CD151,
C5AR1,
C3,
SERPING1,
BUB1,
AOX1,
ANXA11,
ANXA5,
ANXA4,
ANXA1,
ANPEP,
AMPD3,
ALPP,
ALDH2,
ALB,
AHSG,
APLNR,
AGER,
AFM,
ADRB2,
ACVR1,
ACTN3,
ACTL6A,
ACTG2,
ACTG1,
ACR,
ACHE,
ACACA,
APAF1,
APP,
RHOA,
BLM,
BTG1,
BTF3P11,
KLF5,
KLF9,
BPHL,
FOXL2,
BNIP3L,
BNIP3,
BMPR1B,
BMP2,
CEACAM1,
RHOB,
BCR,
BCL7A,
BCL6,
BCAT1,
BAGE,
BACH1,
B2M,
ASS1,
ARNTL,
ARNT,
COX5B,
COX8A,
CREBBP,
MEGF8,
ACSL3,
FANCD2,
FANCA,
F9,
F2RL2,
EYA2,
ETV5,
ETS2,
ETFA,
ESRRB,
ERV3-1,
ERN1,
NR2F6,
EPS8,
EPOR,
EPHB4,
EPHA7,
EPHA5,
EPHA1,
ELK1,
ELF3,
EIF5A,
EIF5,
FANCG,
EFEMP1,
FBP1,
GAST,
KAT2A,
GCHFR,
GBP1,
GBE1,
GATA3,
GATA2,
GAPDH,
GALNT3,
G6PC,
FUT1,
FRA16D,
FEN1,
FRA9E,
FRA7G,
FRA6E,
FOSB,
FMR1,
FLNB,
FLNA,
FOXG1,
FHL2,
FGF9,
EIF4EBP1,
CELSR3,
CRH,
EFNA1,
ACE,
DCN,
DCK,
DCC,
DAPK1,
CD55,
CYP3A5,
CYP2B6,
CYP2A7,
CX3CR1,
CTNND2,
CTNNA1,
CTBP2,
CTBP1,
CSTB,
CSK,
CSF3,
CSE1L,
CS,
CRYZ,
HAPLN1,
CRKL,
CRHR1,
DDB1,
AKR1C1,
DDIT3,
SLC26A3,
EEF1B2P2,
EEF1A1,
E2F6,
E2F3,
DVL1,
DUSP6,
DUSP5,
DUSP4,
DUSP3,
DSC3,
DPYD,
DDX1,
DNM2,
DNAH8,
DMRT1,
DMP1,
DLX5,
DLX4,
DLX1,
DHFR,
DECR1,
DDX10,
POLR2A,
PON2,
PPP1R15A,
RASSF2,
GREB1,
N4BP1,
FAM53B,
MDC1,
PDIA4,
AKAP12,
CLOCK,
NR1D1,
BCAR1,
SPAG7,
CXCL14,
RPH3AL,
KIF23,
RASAL2,
FHL5,
ITM2A,
GSTO1,
QKI,
NTN1,
COX5A,
PLAA,
ITGBL1,
SNAP29,
UTP14C,
MTSS1,
FCN3,
BMS1,
TRIM28,
LRPPRC,
KIF20A,
CERT1,
PTPRU,
HUWE1,
CHAF1A,
FRAT1,
BCL2L11,
AKT3,
THOC1,
RBX1,
FGF19,
GFPT2,
DLEC1,
MFN2,
NUAK1,
SETDB1,
MAGI2,
ELMO1,
SPATA2,
RB1CC1,
SPOCK2,
CD163,
GCNT3,
EBAG9,
NMI,
LIN7A,
INPP4B,
FGF18,
TNFRSF10B,
TNFRSF11A,
DLK1,
SNAP23,
TNFRSF6B,
TNFRSF14,
CD164,
ADAM15,
CTNNAL1,
MBTPS1,
TNKS,
ABCB11,
CHRD,
JRK,
PLPP1,
RUVBL1,
PLA2G4C,
PRKRA,
PDLIM4,
MKNK1,
IQGAP1,
HDAC3,
KAT2B,
USP13,
USP14,
CLDN1,
CLDN6,
PIAS2,
SLC13A2,
DOK2,
UBE2M,
SOCS3,
MPZL1,
F2RL3,
H2AC11,
CDK5R1,
H3C7,
CCNA1,
PRPF4B,
BUD31,
CPNE3,
SLC5A6,
CDC123,
PER2,
APLN,
ALDH1A2,
DHRS2,
EIF1,
FLOT1,
CNMD,
MMRN1,
ZNF365,
FNDC3A,
VASH1,
TUSC2,
ACOT7,
PHB2,
VSIG4,
KLF8,
PTGDR2,
NXPH2,
GALNT6,
NISCH,
PKP3,
ZNF277,
LZTS1,
PSIP1,
CORO1A,
KAT7,
TBC1D8,
BTN3A1,
KATNA1,
TOPBP1,
SIRT2,
DKK1,
TPX2,
LARP1,
LDOC1,
DDX58,
CASP14,
TSPAN12,
ZNF281,
PES1,
ICMT,
ABCB9,
ANGPTL2,
ADNP,
PSD3,
KDM2A,
SYNE1,
FAM168A,
ATP11B,
CIC,
EPB41L3,
CDK19,
TTLL5,
PPRC1,
KDM4B,
FAIM2,
UBE2C,
WWP2,
NBR2,
ABHD2,
PROCR,
LAMTOR5,
UBD,
CIB2,
FBLN5,
CARM1,
CREB3,
HOXB13,
CLEC10A,
TAB1,
PRMT5,
NDC80,
NDRG1,
ANAPC10,
SYCP2,
SEMA3A,
MICU1,
KLF2,
ABCA7,
PAK4,
APC2,
STAG1,
SPRY1,
OLFM4,
AKAP3,
CCT4,
NEU3,
OGFR,
SLC27A2,
COPS5,
KCNQ1OT1,
MLLT11,
TMED2,
TOMM34,
RALBP1,
LYVE1,
PPP1R13L,
FRS2,
SMC2,
WASF3,
CCR9,
IQGAP2,
NES,
GIPC1,
MASP2,
STAG3,
IGF2BP2,
IGF2BP3,
TRIM16,
LGR5,
BARX2,
POU4F3,
SLC6A12,
SLC6A1,
SLC2A5,
SLC2A3,
STIL,
ST3GAL1,
ST6GAL1,
SGK1,
SFTPD,
SFRP5,
SFRP4,
SFRP2,
SEMG1,
SELP,
SEC14L1,
SDC1,
CX3CL1,
CCL25,
CCL22,
CCL15,
CCL8,
CLEC11A,
SCD,
SERPINB3,
SLC6A8,
SLC22A2,
IFITM1,
SLIT3,
TBCE,
CNTN2,
TARS1,
TAP1,
SYT1,
SYK,
SULT1A1,
STAT4,
SRY,
SREBF1,
SRD5A2,
SRC,
SPOCK1,
SOX4,
SOX3,
SOX1,
SOS1,
SOAT1,
SNCA,
SMPD1,
SMARCE1,
HLTF,
SMARCA1,
SAT1,
SAI1,
SALL2,
S100P,
PTPN1,
PTN,
PTK7,
PTK6,
PTHLH,
PTGER3,
PSME1,
PSG5,
PSAP,
PRSS3,
LGMN,
MAP2K2,
MAPK8,
PRKDC,
PRKCB,
PRKACA,
PPP2R5D,
PTPA,
PPP2R2C,
PPP2R2A,
PPP1R1A,
PPIA,
PPARD,
PTPN6,
PTPN13,
PTPRZ1,
RNF2,
S100A11,
S100A7,
S100A6,
S100A4,
RYK,
CLIP1,
RPS7,
RPS6KA1,
MRPL23,
ROBO1,
RNASEL,
PXN,
RNASE2,
RET,
RENBP,
RBBP6,
KDM5A,
PLAAT4,
RARA,
RAP1B,
RAD52,
RAB5A,
TBX15,
ELOB,
TBX3,
ALDH5A1,
H3C1,
H2BC21,
H2AC17,
H2AC16,
H2AC15,
H2AC13,
FZD4,
FZD1,
CDC7,
AXIN2,
TRRAP,
H4C9,
USP9X,
USP11,
MLRL,
CDK2AP1,
YEATS4,
SERPINA3,
MFAP5,
FOSL1,
RASSF7,
NCOA4,
SEM1,
H3C4,
H3C3,
H3C6,
H4C2,
PARG,
RGS5,
SORBS2,
NCK2,
ULK1,
SRPX,
SPOP,
H4C14,
H4C13,
H4C5,
H4C8,
H3C11,
H4C3,
H4C11,
H4C12,
H4C6,
H4C4,
H4C1,
H3C2,
H3C10,
H3C12,
H3C8,
TFEB,
REEP5,
TCF7L2,
IL1R2,
TRPC1,
TRO,
TRAF2,
HSP90B1,
CRISP2,
TPO,
TPM4,
TPD52,
TM7SF2,
TLR1,
TLE3,
NKX2-1,
THRA,
THPO,
THBD,
TGFBR3,
TGFB3,
TFPI,
NR2F2,
TERC,
TEP1,
DYNLT3,
TCF12,
TSC2,
TTF1,
TNFRSF4,
EZR,
PXDN,
SLC30A1,
ZBTB17,
ZNF143,
SF1,
XPC,
XPA,
XDH,
WNT11,
NSD2,
VHL,
UBB,
USP1,
USF1,
UQCRFS1,
UQCRC1,
UMOD,
UGT1A,
SLC35A2,
UCHL3,
UCHL1,
UBC,
USP5
Drugs
—
Registered!
Benign, borderline, or malignant neoplasm involving the ovary
Ovarian tumors, or ovarian neoplasms, are tumors arising from the ovary. They can be benign or malignant (ovarian cancer). They consists of mainly solid tissue, while ovarian cysts contain fluid.
Histopathologic classification
Ovarian tumors are classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis.
The most common forms are:
Type | Subtype | Relative incidence | Percent malignant | Comments | Micrograph |
---|---|---|---|---|---|
Germ cell tumor | Mature cystic teratoma | 46.0% | 0.17% to 2% | Cystic, with elements of all 3 germ layers (endoderm, mesoderm and ectoderm). | |
Immature teratoma | 2.5% | 100% | A teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma. | ||
Other germ cell tumors | 3.0% | Others mainly include dysgerminoma, yolk sac tumor, struma ovarii and squamous cell carcinoma arising from a dermoid cyst, and malignant mixed germ cell tumor. | |||
Surface epithelial-stromal tumor | Serous tumor | 25% | 18.5% | Benign serous tumors of the right ovarian cyst are thinwalled unilocular cysts that are lined by ciliated pseudostratified cuboidal or columnar epithelium. | |
Mucinous tumor | 15% | 8.8% | Benign mucinous tumors of the ovary consist of simple, nonstratified columnar epithelium with basally-located hyperchromatic nuclei and resemble gastric foveolar epithelium. | ||
Endometrioid tumor | 1% | Almost 100% | Tubular glands, resembling endometrium. | ||
Other surface-epithelial tumors | 1.5% | Others include mainly malignant mixed mullerian tumor, Brenner tumor and mixed epithelial tumor. | |||
Sex cord-stromal tumor | Ovarian fibroma | 1.5% | 0% | Spindle-shaped fibroblastic cells and abundant collagen. | |
Adult granulosa cell tumor | 1% | Almost 100% | Small, bland, cuboidal to polygonal cells in various patterns. | ||
Other sex cord-stromal tumors | 1% | Others include mainly juvenile granulosa cell tumor, thecoma and sclerosing stromal tumor | |||
Secondary/metastatic) tumor | 2% | 100% | Usually from breast cancer, colon cancer, endometrial cancer, stomach cancer or cervical cancer. |
Mixed tumors contain elements of more than one of the above classes of tumor histology.