Kbg Syndrome

KBG syndrome is a genetic disease that is the result of a mutation in the ANKRD11 gene. Features include unusually large upper front teeth (macrodontia), wide, short skull (brachycephaly), widely spaced eyes (hypertelorism), and wide eyebrows that may grow together in the middle (synophrys).

The syndrome was first described by Herrmann in 1975 in three distinct families. Herrmann proposed the name KBG syndrome after the initials of affected families last names.