Dermal Ridges, Nelson Syndrome

Clinical Features

David (1973) described a family, with the surname Nelson, in which a novel dermatoglyphic syndrome occurred in a mother and 3 of her children. The palmar features were the same as those in ROES (125550), but the only striking feature in the fingerprints was that the loops were rather 'pointed' and came near to being tented arches.

Inheritance

David (1973) suggested that this dermatoglyphic trait is inherited in an autosomal dominant manner.

Mapping

David et al. (1973) performed linkage analysis in the family with Nelson syndrome and found a low positive lod score with the Duffy blood group locus (FY; 110700).