Syndromes Affecting The Heart
A syndrome is a set of medical signs and symptoms that are correlated with each other. A syndrome can affect one or more of body systems. Different syndromes affect different groups of organs. This is a list of syndromes that may affect the heart. Syndromes affecting primarily the heart are written in bold letters.
Syndrome | Cause | cardiac symptoms | Other symptoms or organs affected | Notes |
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1q21.1 deletion syndrome | genetic (Chromosome 1) | Cardiovascular anomalies are present in 30% of the cases (for example anomalous origin of the coronary artery in "Class II-deletion") |
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DiGeorge syndrome | genetic (Chromosome 22) | commonly interrupted aortic arch, truncus arteriosus and tetralogy of Fallot |
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Acute coronary syndrome | Commonly associated with three clinical manifestations: ST elevation myocardial infarction (STEMI, 30%), non ST elevation myocardial infarction (NSTEMI, 25%), or unstable angina (38%) | |||
Adams–Nance syndrome | maybe disturbance in glycine metabolism | persistent tachycardia, paroxymal hypertension |
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Alagille syndrome | genetic (Autosomal dominant inheritance: loss of function mutations in either JAG1 or NOTCH2) | Congenital heart problems e.g. pulmonary artery stenosis (common), Tetralogy of Fallot, overriding aorta, ventricular septal defect; and right ventricular hypertrophy. | Liver (jaundice, pruritus, hepatosplenomegaly, acholia, xanthoma) | |
Andersen–Tawil syndrome | ||||
Antley–Bixler syndrome | ||||
Barth syndrome | ||||
Brugada syndrome | ||||
Cantú syndrome | genetic (Chromosome 12, autosomal dominant) | |||
Cardiac syndrome X | ||||
Cardiorenal syndrome | Kidney | |||
Cat eye syndrome | ||||
CHARGE syndrome | ||||
Coffin–Lowry syndrome | genetic (RPS6KA3 gene mutation, Chromosome X) | |||
Costello syndrome | ||||
Down syndrome | genetic (Chromosome 21) | |||
Dressler syndrome | autoimmune inflammatory reaction secondary to MI. | |||
Edwards syndrome | genetic (Chromosome 18) | |||
Eisenmenger's syndrome | ||||
Ellis–van Creveld syndrome | ||||
Emanuel syndrome | ||||
HEC syndrome | ||||
Heyde's syndrome | ||||
Ho–Kaufman–Mcalister syndrome | ||||
Holt–Oram syndrome | ASD, and a first degree heart block. | |||
Hypoplastic left heart syndrome | ||||
Jacobsen syndrome | genetic (Chromosome 11q deletion) | |||
Jaffe–Campanacci syndrome | ||||
Jervell and Lange-Nielsen syndrome | genetic (autosomal recessive) | a type of long QT syndrome | ||
Kabuki syndrome | ||||
Kearns–Sayre syndrome | ||||
Long QT syndrome | ||||
Lutembacher's syndrome | ||||
Malpuech facial clefting syndrome | ||||
Marden–Walker syndrome | ||||
Marfan syndrome | ||||
McKusick–Kaufman syndrome | ||||
McLeod syndrome | ||||
Noonan syndrome | ||||
Noonan syndrome with multiple lentigines | ||||
Ortner's syndrome | ||||
Bouveret Hoffmann syndrome | another name for "Paroxysmal tachycardia" | |||
Patau syndrome | genetic (Chromosome 13) | |||
Pre-excitation syndrome | ||||
Romano–Ward syndrome | ||||
Scimitar syndrome | ||||
Shone's syndrome | ||||
Short QT syndrome | ||||
Sick sinus syndrome | ||||
Taussig–Bing syndrome | double outlet right ventricle (DORV) and subpulmonic VSD. | a cyanotic congenital heart defect | ||
Timothy syndrome | ||||
Townes–Brocks syndrome | ||||
Triploid syndrome | ||||
Turner syndrome | ||||
VACTERL syndrome | ||||
Wellens' syndrome | ||||
Williams syndrome | ||||
Wolff–Parkinson–White syndrome | ||||
Zunich–Kaye syndrome | ||||
Lown–Ganong–Levine syndrome |