Familial Isolated Clinodactyly Of Fingers
Watchlist
Retrieved
2021-01-23
Source
Trials
—
Genes
ABL1,
TFAP2B,
TFAP2A,
TBX22,
IGF2,
INTU,
NSMF,
TCTN3,
KIFBP,
PHGDH,
PGAP2,
MKS1,
CCDC22,
ANKRD11,
NIN,
TMEM216,
POMP,
MAGEL2,
BCOR,
SIN3A,
POC1A,
NPAP1,
ZMPSTE24,
MED12,
HUWE1,
MKRN3-AS1,
ALG3,
CD96,
SF3B4,
IRX5
ABL1,
TFAP2B,
TFAP2A,
TBX22,
IGF2,
INTU,
NSMF,
TCTN3,
KIFBP,
PHGDH,
PGAP2,
MKS1,
CCDC22,
ANKRD11,
NIN,
TMEM216,
POMP,
MAGEL2,
BCOR,
SIN3A,
POC1A,
NPAP1,
ZMPSTE24,
MED12,
HUWE1,
MKRN3-AS1,
ALG3,
CD96,
SF3B4,
IRX5,
COG5,
CLCF1,
SLC35A1,
COLEC10,
STAMBP,
PUF60,
CHSY1,
SPART,
MED13L,
NCAPG2,
PHIP,
ALX3,
CKAP2L,
TRAF7,
COG8,
PIGO,
PIGY,
G6PC3,
PGAP3,
PWAR1,
ESCO2,
SPRTN,
ARID2,
PIGW,
FAM149B1,
SNORD115-1,
HEPHL1,
KIF7,
PWRN1,
KIAA1109,
ITCH,
YY1AP1,
SNX14,
SLC29A3,
PIGV,
IFT122,
ERMARD,
MCTP2,
KIF15,
NUP107,
WDR35,
CLPB,
TRPV4,
PIEZO2,
XYLT1,
NXN,
CPLANE1,
FAT4,
FBXO11,
KIAA0753,
CEP57,
PUM1,
GJA1,
IGF1,
IGF1R,
INS,
PDX1,
IPW,
KCNJ11,
LMNA,
SMAD4,
NDN,
NEK1,
NPR2,
ROR2,
PAH,
PAX3,
PDE6D,
HNRNPK,
GCK,
POLE,
FGD1,
ATRX,
BRCA1,
BRAF,
CDC6,
CDC42,
CDH1,
CSNK2A1,
DDX11,
DLX3,
DSP,
DVL1,
DVL3,
EZH2,
BPTF,
GPC4,
PIGL,
PIK3R1,
POR,
WNT7A,
PCGF2,
ALX1,
RBM10,
KDM5C,
SMC1A,
NAA10,
OFD1,
CDK10,
CDK13,
DCHS1,
CACNA1G,
HERC2,
RAB11B,
NOG,
TRIP12,
MAP2K1,
MKRN3,
WNT5A,
TTPA,
PTPN11,
DPF2,
RPL10,
SNRPN,
SOX4,
SOX5,
SOX11,
SSR4,
ABCC8,
MAP3K7,
TBX5,
TCF4,
TNNT3,
TRIO,
SNORD116-1,
KCNJ2,
WDR20,
PHF6,
TGDS,
FGFR2
Drugs
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Registered!
Familial isolated clinodactyly of fingers is a rare, genetic, non-syndromic, congenital limb malformation disorder characterized by angulation of a digit in the radio-ulnar (coronal) plane, away from the axis of joint flexion-extension, in several members of a single family with no other associated manifestations. Deviation is usually bilateral and commonly involves the fifth finger. Affected digits present trapezoidal or delta-shaped phalanges on imaging.