Cutaneous T-Cell Lymphoma
Watchlist
Retrieved
2022-04-26
Source
Trials
—
Genes
CTLA4,
CD28,
TP53,
FAS,
CDKN2A,
STAT5B,
PLCG1,
MCL1,
NFKB2,
IRF4,
MIR22,
ZEB1,
BAX,
TNFAIP3,
CTCF,
PRKCQ,
RHOA,
ATM,
ARID1A,
FGFR3,
CARD11,
DNMT3A,
BRAF,
TRBV20OR9-2,
HDAC9,
IL15,
TNFRSF1B,
TNFRSF8,
BCL2,
STAT3
CTLA4,
CD28,
TP53,
FAS,
CDKN2A,
STAT5B,
PLCG1,
MCL1,
NFKB2,
IRF4,
MIR22,
ZEB1,
BAX,
TNFAIP3,
CTCF,
PRKCQ,
RHOA,
ATM,
ARID1A,
FGFR3,
CARD11,
DNMT3A,
BRAF,
TRBV20OR9-2,
HDAC9,
IL15,
TNFRSF1B,
TNFRSF8,
BCL2,
STAT3,
CCR4,
IL10,
IL2,
JAK3,
IL4,
MIR155,
IFNG,
IL7,
KIR3DL2,
STAT5A,
TOX,
IL17A,
NOTCH1,
IL5,
HDAC1,
CCR6,
FOXP3,
SOAT1,
CDKN2B,
CXCR4,
CCR10,
DNER,
NAV3,
ITGAM,
CTAGE1,
IFNA1,
ISG20,
TSPYL2,
IFNA13,
IL16,
MDM2,
IL2RA,
JUNB,
ITGB2,
JAK1,
MIR150,
CD164,
CTNNB1,
TNF,
XPR1,
IL31,
CCL20,
MIR203A,
MIR205,
RARA,
TRBV16,
STAT6,
SYCP1,
TRB,
CTDSP1,
MUC1,
TRG,
TRGC1,
TGFB1,
SCPEP1,
THBS1,
SOCS3,
CFLAR,
VEGFA,
AHI1,
MYC,
STAT4,
PTPN6,
PIK3CG,
PIK3CD,
TRBC1,
MAPK3,
PIK3CB,
PIK3CA,
PAK1,
SAMHD1,
BRD4,
HDAC6,
OPRM1,
ERVW-1,
IL22,
NRAS,
AKT1,
SATB1,
NFKB1,
TRBV7-9,
RAD23B,
TP63,
THEMIS,
CD40LG,
IL1A,
FOS,
IL1B,
CBL,
CCR3,
GATA3,
PPP1R2C,
IL6,
CXCL8,
TARP,
IL17F,
DPP4,
FKBP4,
CXCL10,
CD47,
EZH2,
ATN1,
IL13,
H3P10,
ANG,
BIN1,
RUNX3,
MIR122,
DLEU1,
MIRLET7I,
SUPT7L,
NFKBIZ,
CCL26,
CIB1,
MRPL28,
POSTN,
CD226,
MALAT1,
CCL27,
SUB1,
RAB40B,
CKAP4,
MIR126,
SART3,
MIR200B,
ERVK-20,
TNFSF10,
TNFSF9,
H3P42,
H3P9,
HDAC3,
ARHGEF7,
LINC02605,
USP2,
ERVK-32,
ERVK-18,
MIR4433A,
MIR200C,
MIR711,
DEFB4B,
KIR2DS2,
IL32,
STK17B,
MIR337,
MIR223,
SIRT2,
MIR214,
MIR21,
PSIP1,
SIRT1,
TPX2,
KRT20,
SPZ1,
ASCC2,
ARHGAP24,
LBH,
TXNDC5,
ASCC1,
HM13,
HDAC7,
GDE1,
BCL11A,
SOX18,
CHFR,
CXCL17,
HDAC8,
MYDGF,
TIGAR,
NLN,
PREX1,
MUL1,
IL22RA1,
IL21,
SOCS1,
BCL11B,
IL25,
IL20,
HAVCR2,
TSLP,
TBX21,
PDCD11,
ARC,
DICER1,
CADM1,
POT1,
PRSS55,
CBLL2,
SND1,
BBC3,
CARMIL2,
IL31RA,
IL17B,
H4-16,
GTSF1,
APOA5,
FCRL3,
GNG8,
DROSHA,
NXT1,
PYCARD,
CD274,
IL19,
OPN4,
JAG1,
RRM2,
NCOA1,
HSP90AA1,
FLT4,
FOSB,
FOSL2,
FTH1,
GATA6,
CXCR3,
GSTM1,
GTF2H4,
HDAC2,
HLA-C,
HLA-DQB1,
HLA-DRB1,
HMGB1,
NR4A1,
ICAM3,
ZNF195,
IFNA2,
IKBKB,
IL2RG,
IL3RA,
IL9,
TNFRSF9,
IL18,
IDO1,
ITGB7,
JAK2,
JUN,
JUND,
KIT,
KRAS,
FLG,
FOXO3,
FKBP5,
EPHA4,
ANXA5,
BIRC5,
APOC3,
FASLG,
ASS1,
CCND1,
BCL6,
BCL7A,
BLK,
CASP1,
CASP3,
CASP9,
CCND2,
CD5,
MS4A1,
CD22,
CD80,
CD40,
CD44,
CDK2,
CDKN1B,
CDKN1C,
CHI3L1,
CCR7,
CSF2,
CUX1,
DECR1,
DEFB4A,
DNMT1,
LAIR2,
LCK,
LGALS1,
RAG1,
RB1,
REG1A,
RELB,
RPE65,
S100A7,
CCL17,
CCL18,
CCL21,
CCL22,
SDC4,
SELL,
SELPLG,
PMEL,
SST,
STAT1,
STAT2,
AURKA,
MAP3K7,
CNTN2,
PPP1R11,
TDO2,
THBS4,
TP73,
CRISP2,
NR2C2,
TRAF2,
TWIST1,
TNFSF4,
UVRAG,
RAG2,
RAC1,
LGALS9,
PVR,
LTA,
MBL2,
MDM4,
MIA2,
MGMT,
CXCL9,
MT1E,
MTAP,
NCAM1,
NFATC1,
NTS,
NTSR1,
OAS3,
PAEP,
PRKN,
PCM1,
PDGFRA,
PGF,
ABCB1,
PIM1,
PKM,
PLK1,
PLS3,
PTEN,
PTH,
PTGS2,
PTPN11,
PTPRC,
PTPRG,
H3P40
Drugs
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Registered!
Cutaneous T-cell lymphomas (CTCLs) are a group of disorders characterized by an abnormal accumulation of cancerous T-cells (a type of white blood cells) in the skin resulting in an itchy, red rash that can thicken or form a tumor. CTCLs belong to a larger group of disorders known asnon-Hodgkin's lymphomas. The most common types are mycosis fungoides and Sézary syndrome. In some cases, cancerous T-cells may spread to the lymph nodes and eventually to other body tissues and organs, potentially resulting in life-threatening complications. The specific signs and symptoms vary from person to person. The exact cause of these conditions is unknown.