Gingival Fibromatosis-Facial Dysmorphism Syndrome

A very rare syndrome characterized by the association of gingival fibromatosis and craniofacial dysmorphism.

Epidemiology

It has been described in two sibs.

Clinical description

Craniofacial dysmorphism consists of relative macrocephaly, bushy eyebrows with synophris, hypertelorism, downslanting palpebral fissures, flattened nasal bridge and high arched palate. The patients have normal intellect.

Genetic counseling

The condition seems to be hereditary, transmitted as an autosomal recessive trait.