Autoimmune Polyendocrinopathy Type 2

Watchlist

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Retrieved

2021-01-23

Source

Orphanet

Trials

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Genes

AIRE, FOXP3, HLA-DRB1, NUDT11, RBM45, KLK3, CTLA4, HLA-DQA1, SH2B2, HT, HLA-DQB1, IL2RA, IL15, STAT4

Drugs

Hydrocortisone ( ALKINDI ), Hydrocortisone (modified release tablet) ( PLENADREN ), Prasterone

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A rare, endocrine disease characterized by autoimmune Addison disease associated with autoimmune thyroid disease or type I diabetes mellitus, or both, and without chronic candidiasis. Additional endocrine (hypogonadism, hypoparathyroidism) and non-endocrine diseases (vitiligo, autoimmune hepatitis, autoimmune gastritis, pernicious anemia, and myasthenia gravies) may be present.