Mental Retardation, X-Linked, With Craniofacial Dysmorphism

Hyde-Forster et al. (1992) described 2 maternal half brothers with moderate mental retardation, plagiocephaly, brachycephaly, prominent forehead, and coarse facial features. Two sisters of the proband's mother were mentally retarded, but did not have any dysmorphic features. Hyde-Forster et al. (1992) proposed that this complex was a 'new' X-linked mental retardation syndrome.