Mevalonic Aciduria Watchlist (log in to enable) Retrieved 2021-01-23 Source Orphanet Trials — Genes MVK, HMGCR, NLRP3, TNF, MEFV, IL1B, RAC1, TNFRSF1A, RHOA, SEC23B, NLRC4, ADA2, PMVK, SAA1, PSTPIP1, FDFT1, IL1A, IFNG, GRID2, MMAB Drugs — Interested in hearing about new therapies? Registered! A rare, very severe form of mevalonate kinase deficiency (MKD) characterized by dysmorphic features, failure to thrive, psychomotor delay, ocular involvement, hypotonia, progressive ataxia, myopathy, and recurrent inflammatory episodes.