Skin Infection

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Retrieved

2021-01-18

Source

Wikipedia

Trials

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Genes

SLC9A6, TLR2, FLG, TNF, IL17A, PAGR1, IL1B, IL4, FAM3B, DOCK8, IL13, GAST, GALNS, VWF, TYR, TST, MAPK1, CFLAR, STAT6, STAT3, RFC1, RARRES2, AIMP2, ADAM10, GRAP2, CXCL14, PLG, AHSA1, CABIN1, RNF19A

SLC9A6, TLR2, FLG, TNF, IL17A, PAGR1, IL1B, IL4, FAM3B, DOCK8, IL13, GAST, GALNS, VWF, TYR, TST, MAPK1, CFLAR, STAT6, STAT3, RFC1, RARRES2, AIMP2, ADAM10, GRAP2, CXCL14, PLG, AHSA1, CABIN1, RNF19A, POLDIP2, SETD2, IRAK4, TLR7, CD177, TNS3, NBEAL1, AGBL2, RNASE7, PPARG, MPO, PCP4, HP, CD36, LTB4R, CRK, CRP, MAPK14, CTLA4, EDNRB, EGFR, ELN, F5, FN1, GAPDH, GRN, HIF1A, HSPD1, MYO9B, IDE, IFNA1, IFNA13, IFNG, IL1A, IL2, IL6, IL9, IL15, LCT, LGALS3, MAP2, ADSS2, RNR1, COPD

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A skin infection is an infection of the skin in humans and other animals, that can also affect the associated soft tissues such as loose connective tissue and mucous membranes. They comprise a category of infections termed skin and skin structure infections (SSSIs), or skin and soft tissue infections (SSTIs), and acute bacterial SSSIs (ABSSSIs). They are distinguished from dermatitis (inflammation of the skin). although skin infections can result in skin inflammation.

Causes

Bacterial

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Example of cellulitis showing 3+ edema of left leg

Bacterial skin infections affected about 155 million people and cellulitis occurred in about 600 million people in 2013. Bacterial skin infections include:

Cellulitis, a diffuse inflammation of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin
Erysipelas, an acute infection of the deep epidermis often with lymphatic spread, almost exclusively caused by beta-hemolytic streptococcus bacteria
Folliculitis, an infection of the hair follicle
Impetigo, a highly contagious ABSSSI (acute bacterial skin and skin structure infection) common among pre-school children, primarily associated with the pathogens S. aureus and S. pyogenes

Fungal

Fungal skin infections may present as either a superficial or deep infection of the skin, hair, and/or nails. Mycetoma are a broad group of fungal infections that characteristically originate in the skin and subcutaneous tissues of the foot. If not treated appropriately and in a timely fashion mycetoma infections can extend to deeper tissues like bones and joints causing osteomyelitis. Extensive osteomyelitis can necessitate surgical bone resections and even lower limb amputation. As of 2010, they affect about one billion people globally.

Parasitic

Parasitic infestations of the skin are caused by several phyla of organisms, including Annelida, Arthropoda, Bryozoa, Chordata, Cnidaria, Cyanobacteria, Echinodermata, Nemathelminthes, Platyhelminthes, and Protozoa.

Viral

Virus-related cutaneous conditions caused by these obligate intracellular agents derive from both DNA and RNA viruses.