Autoimmune Polyendocrinopathy
Watchlist
Retrieved
2021-01-23
Source
Trials
—
Genes
AIRE,
FOXP3,
GPI,
F2,
APOH,
F3,
NUDT11,
HLA-DRB1,
TLR4,
LMNA,
NUDT10,
MTOR,
ANXA5,
LRP8,
RBM45,
SERPINE1,
F5,
TNF,
SH2B2,
F2R,
CPB2,
HLA-DQA1,
NOD2,
TLR7,
KLK3,
TFPI,
MPO,
MIR19B1,
VCAM1,
VIM
AIRE,
FOXP3,
GPI,
F2,
APOH,
F3,
NUDT11,
HLA-DRB1,
TLR4,
LMNA,
NUDT10,
MTOR,
ANXA5,
LRP8,
RBM45,
SERPINE1,
F5,
TNF,
SH2B2,
F2R,
CPB2,
HLA-DQA1,
NOD2,
TLR7,
KLK3,
TFPI,
MPO,
MIR19B1,
VCAM1,
VIM,
MTHFR,
TLR2,
SELPLG,
NR1I2,
BLK,
MIR20A,
PLG,
ANXA2,
PWAR1,
F2RL1,
CD36,
CXCL8,
STAT4,
MARK2,
BANK1,
SLC52A1,
SLC52A2,
IL17A,
H3C1,
CLIP2,
H3C4,
MOK,
SLC20A1,
TSHR,
RELA,
ROS1,
TERC,
SYT1,
S100A10,
CCL2,
SELE,
H3C6,
STAT1,
H3C3,
ADH1A,
H3C11,
H3C8,
ANXA8,
LINC01193,
IFNL1,
BHLHA15,
ASPRV1,
MUC15,
HT,
WNK1,
GORASP1,
APOBEC3G,
TLR8,
NXPH1,
FLVCR1,
SLC17A5,
IFI44L,
TNFSF13B,
CD226,
PROS1,
C1D,
AKR1A1,
GTPBP1,
H3C7,
SKAP2,
PLA2G6,
H3C2,
H3C10,
H3C12,
PTGS1,
PC,
PROC,
GNAS,
EGF,
EMD,
ENG,
EPO,
F9,
GCY,
GP1BA,
DDIT3,
GYPB,
CFH,
HLA-A,
HLA-B,
HLA-DMA,
HLA-DPB1,
EDN1,
CYBB,
PPARG,
TSPO,
AKT1,
AMH,
APP,
APRT,
AQP4,
SERPINC1,
C4A,
CHRM3,
C5,
CAPS,
ENTPD1,
CD59,
CDR1,
CDR2,
HLA-DRB4,
HMGB1,
HSPA4,
PF4V1,
NPHP1,
NT5E,
TNFRSF11B,
SERPINB2,
AGER,
PF4,
PGF,
HSPA5,
PIK3CA,
PLA2G1B,
PLA2G2A,
PLSCR1,
PON1,
POU1F1,
NOS3,
COX3,
MSN,
MLH1,
MFAP1,
CD46,
MBL2,
LCT,
ITGB2,
ITGAM,
ISG20,
IRF5,
IL6,
IL2RA,
IGHG3,
IGF1,
ICAM1,
C20orf181
Registered!
A group of rare endocrine diseases characterized by autoimmune activity against more than one endocrine organ, with possible additional involvement of non-endocrine organs. Autoimmunity is typically directed against different target antigens in different tissues. The two more common autoimmune polyendocrine syndromes (APS), APS type 1 and type 2, have a strong genetic background and have Addison's disease as a major feature. The group furthermore includes APS type 3 and type 4.