Kawasaki Disease

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Retrieved

2022-04-26

Source

Gard

Trials

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Genes

FCGR2A, ITPKC, BLK, CD40, KCNN2, NEBL, MED30, MDGA1, ATP5MF, NAALADL2, FHAD1, TECRL, SLC35F5, ZSCAN25, CRP, CENPU, PTCD1, TNF, SGCD, MESP2, IL10, PREX1, LDLRAD3, ZNF618, IL6, IRF8, DAB1, ATP5MF-PTCD1, IL1A, IL1B, MIA, MIA-RAB4B, IL1RAP, FHAD1-AS1, BUD31, SETBP1, VEGFA, MMP9, IL18, CASP3, ALB, HLA-DRB1, IL4, IL1RN, ACE, PECAM1, IL17A, HSPD1, MIR223, ORAI1, SMAD3, IFNG, CCR5, MBL2, CD40LG, VCAM1, CD14, CD68, S100A9, NLRP3, RBM45, HMGB1, HAMP, HLA-B, HLA-C, CCL2, S100A12, GPT, CCL3L1, FCGR3B, FCGR2B, TNFRSF1A, CCR2, IL6ST, FOXP3, SEMA6A, HSPA14, GOPC, RETN, IL2RA, PTX3, MMP3, S100A8, ISG20, SLC11A1, SLC8A1, LTA, CCL5, MPO, SDC1, MEFV, IL2, MMP2, MIF, FBLIM1, IL1R1, TGFB2, CDR3, AIF1, TRIP10, VWF, CSF3, ABCC4, CYP2C9, NOD1, ESR1, FCN1, FLT1, TIMP2, LINC01194, TGFBR2, MIR145, HMOX1, TGFB1, HLA-A, HLA-DQA1, COPB2, CD209, IL22, CCL4L2, AIM2, STOML1, AMACR, KLRK1, POT1, SPATA2, MAP7, SPAG9, NMNAT2, PLCB1, SUCO, SOCS3, IL23A, ADA2, FCMR, PYCARD, WDR1, ATP6AP2, UTS2, HCP5, TNFSF13B, LILRB4, ADAMTS13, POSTN, GCA, ANP32B, FGF21, PHLPP1, SP140, TLR6, NLRP1, IL17D, TRBV6-5, ABO, ABCC11, TET2, MIR155, MIR222, MIR21, MIR200C, MIR186, MIR183, MIR182, MIR146A, LCE3B, MIR134, MIR125A, MIRLET7I, CCL4L1, IL31, PEAR1, MIR27A, MIR27B, MIR31, MIR320A, MIR371A, WG, TIFAB, MIR483, BRD7P2, MIR671, KIR2DS2, CD24, AD12, RPL17-C18orf32, KLRC4-KLRK1, MIR4515, MTCO2P12, LCE3C, NLRP14, PBK, CLEC7A, GGCT, VKORC1, WNK1, P2RY12, GORASP1, EBF2, CDH22, OR10A4, IL21, NLRC4, PELI1, CD177, BTNL2, MYDGF, NLRX1, GSDMD, ULBP1, ZBP1, SYTL1, CD84, NLRP12, CLEC6A, SFXN1, C1QTNF1, GRIN3A, LRG1, TPH2, HT, SAMD9L, IL27, CERS6, NR1I2, TAC1, TNFSF13, SMAD7, HP, HLA-G, HLA-E, HLA-DQB2, HLA-DPB1, HLA-DOB, HLA-DOA, HIF1A, HGF, GZMB, CXCL2, NR3C1, GLS, GLB1, KAT2A, HSD11B2, HSPA5, TNC, KDR, SMAD5, SMAD1, LDHA, KLRC1, KIR3DL2, KIR2DL2, ITPR3, ICAM1, INSR, IL15, IL12B, CXCL8, IL7, IGF1R, GATA3, GAPDH, FUT1, ANGPT1, CACNB2, VPS51, STS, AQP1, APOB, ANGPT2, AKT1, CAT, AGTR1, AGT, JAG1, AGER, ADM, ADA, CASP4, SEPTIN7, VEGFD, CYP2E1, FCER2, BPTF, ERBB2, EPHB2, ELN, ELAVL2, CTNNB1, CEACAM5, CTLA4, CCN2, MAPK14, COL11A2, CCR3, CHI3L1, SMAD6, MICB, BECN1, MMP11, TIMP4, TIMP1, THBD, TFRC, TRBV20OR9-2, ZEB1, TBXA2R, ACHE, SYT1, ABCC8, SULT1A1, STAT1, SRC, SNCA, SIX1, TLR1, TLR2, TLR4, VEGFC, NCOA1, FGF23, PLA2G7, ABHD16A, PRRC2A, SEMA3B, VDR, TNFAIP3, UCP2, TYK2, TNFRSF4, TNFSF4, TUBA3C, TP53, ST6GAL1, SELP, SELE, NGF, SERPINE1, OTX2, OLR1, NR4A2, NOTCH4, NOS2, NFATC2, PDE2A, NFATC1, NCAM1, MYO5B, COX2, MMP13, MMP12, PDCD1, PGK1, CCL17, PTGS2, CCL4, SCN3A, SAG, RPL17, RELA, NECTIN1, MAP2K7, SERPINA1, MAPK3, MAPK1, PRF1, PPARG, PPARD, PLCB4, LINC02605

Drugs

Human normal immunoglobulin ( GAMMAGARD, GAMMAGARD LIQUID, GAMMAPLEX, ENDOBULINE, FLEBOGAMMA DIF, HIZENTRA, HYQVIA, KIOVIG, OCTAGAM, INTRAGLOBIN F, PRIVIGEN, SANDOGLOBULINE, TEGELINE )

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Kawasaki disease is a disease that involves inflammation of the blood vessels. It is typically diagnosed in young children, but older children and adults can also develop this condition. Kawasaki disease begins with a fever that lasts at least five days. Other classic symptoms may include red eyes, lips, and mouth; rash; swollen and red hands and feet; and swollen lymph nodes. Sometimes the disease affects the coronary arteries which carry oxygen-rich blood to the heart, which can lead to serious heart problems. Kawasaki disease occurs most often in people of Asian and Pacific Island descent. The cause of Kawasaki disease is unknown. An infection along with genetic factors may be involved. Treatment includes intravenous gamma globulin and high doses of aspirin in a hospital setting. Prognosis is generally very good, but in cases of heart complications it depends on the severity of the coronary disease.