Juvenile Myoclonic Epilepsy
Watchlist
Retrieved
2021-01-23
Source
Trials
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Genes
EFHC1,
GABRA1,
CACNB4,
JRK,
KCNQ3,
CLCN2,
GABRD,
CILK1,
BRD2,
CTF1,
CHRNA4,
EJM2,
GABRG2,
GJD2,
GRM4,
SCN1A,
CSTB,
GABRB3,
SEC14L2,
ME2,
CHRNA7,
KCNQ2,
KCND3,
TRPM2,
IGHE,
TAP1,
EFHC2,
GJA8,
GABBR1,
REM1
EFHC1,
GABRA1,
CACNB4,
JRK,
KCNQ3,
CLCN2,
GABRD,
CILK1,
BRD2,
CTF1,
CHRNA4,
EJM2,
GABRG2,
GJD2,
GRM4,
SCN1A,
CSTB,
GABRB3,
SEC14L2,
ME2,
CHRNA7,
KCNQ2,
KCND3,
TRPM2,
IGHE,
TAP1,
EFHC2,
GJA8,
GABBR1,
REM1,
RMDN1,
PADI4,
LGSN,
BCL9,
SLC12A5,
RMDN3,
LRRC1,
SYBU,
CPA6,
CLOCK,
MMEL1,
DHX40,
NPL,
CHRFAM7A,
RBM45,
RMDN2,
MED19,
SLC12A6,
SELENOP,
ABCG2,
KCNJ3,
CASR,
DNMT1,
ATN1,
EXT1,
F2,
GABRA5,
HLA-DPB1,
HLA-DQA1,
HLA-DRB1,
HLA-F,
KCNJ6,
TOP3B,
CFP,
ABCB1,
PLXNB1,
HCN2,
SLC6A4,
SLC12A2,
TFAP2B,
ALDH5A1,
PER3,
PER2,
STIN2-VNTR
Drugs
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Registered!
Juvenile myoclonic epilepsy is the most common hereditary idiopathic generalized epilepsy syndrome and is characterized by myoclonic jerks of the upper limbs on awakening, generalized tonic-clonic seizures manifesting during adolescence and triggered by sleep deprivation, alcohol intake, and cognitive activities, and typical absence seizures (30% of cases).