Keratoderma Hereditarium Mutilans With Ichthyosis

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Retrieved

2021-01-23

Source

Orphanet

Trials

—

Genes

LORICRIN, KDR, LOXL2, VEGFA

Drugs

Liarozole, Tazarotene

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Keratoderma hereditarium mutilans with ichthyosis is a diffuse palmoplantar keratoderma characterized by honeycomb palmoplantar hyperkeratosis associated with pseudoainhum of the fifth digit of the hand, ichthyosis and deafness. Keratoderma hereditarium mutilans with ichthyosis follows an autosomal dominant mode of transmission.