Vestibular Schwannoma

Watchlist

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Retrieved

2021-01-23

Source

Orphanet

Trials

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Genes

NF2, HRAS, KARS1, PRKAR1A, ERBB2, COX8A, LZTR1, EGFR, VEGFA, CCND1, HEY2, SMARCB1, SMS, ERBB3, CXCR4, CRLF1, RSS, AKT1, TNF, TP53, TSC1, PTGS2, PTEN, PCNA, COX2, CD274, HGF, MIR21, FGF2, TGFB1

NF2, HRAS, KARS1, PRKAR1A, ERBB2, COX8A, LZTR1, EGFR, VEGFA, CCND1, HEY2, SMARCB1, SMS, ERBB3, CXCR4, CRLF1, RSS, AKT1, TNF, TP53, TSC1, PTGS2, PTEN, PCNA, COX2, CD274, HGF, MIR21, FGF2, TGFB1, ABCA2, CAV1, ABR, EGF, EIF4G1, ASL, ABCG2, CD163, AQP6, ARTN, NRP1, KLF11, AR, HBN1, SEMA3B, WT1, BASP1, BCL2, TSC2, BDNF, BRAF, CASP8, THBS1, CAT, TGFA, PRDX2, PIEZO1, DCTN6, ZNRD2, SPP1, MTCO2P12, TMED7-TICAM2, MIR451A, TICAM2, ZAR1, IL34, AQP1, NLRP3, PPP1R14A, FSD1L, FSD1, TRPV4, HMHB1, MIB1, TMEM165, SMG8, TMED7, AQP2, AQP4, PEG10, RASSF1, STAT1, SOD2, ENG, CCND3, KRT81, KRAS, CSF1, ITGA4, IL6, IFI27, CYP2E1, NRG1, GSTP1, GDNF, MTOR, FOLH1, EIF4A1, FGF1, ESR1, ERBB4, EIF4A2, EIF4E, EPOR, EPO, EPHB2, KRT86, LAMP2, LIMK1, SLC26A4, SLC12A2, SCN5A, RB1, CCNH, CD44, PSMD9, MAPK1, CDKN1A, PIK3CA, CDKN1B, MDM2, NRTN, NOS3, ABCA3, NF1, CDKN2A, MMP9, MMP2, MKI67, MET, H3P23

Drugs

Epstein-Barr virus-specific autologous cytotoxic T lymphocytes, N-hydroxy-4-(3-methyl-2-(S)-phenyl-butyrylamino)benzamide

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Vestibular schwannoma is a rare tumor of the posterior fossa originating in the Schwann cells of the vestibular transitional zone of the vestibulocochlear nerve that can be benign, small, slow growing and asymptomatic or large, faster growing and aggressive and potentially fatal, presenting with symptoms of hearing and balance impairment, vertigo, ataxia, headache and fifth, sixth or seventh cranial nerve dysfunction and facial numbness.