List Of Hepato-Biliary Diseases

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Retrieved
2021-01-18
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Hepato-biliary diseases include liver diseases and biliary diseases. Their study is known as hepatology.

Liver diseases

Viral hepatitis

  • Acute hepatitis A
  • Acute hepatitis B
  • Acute hepatitis C
  • Acute hepatitis D – this is a superinfection with the delta-agent in a patient already infected with hepatitis B
  • Acute hepatitis E
  • Chronic viral hepatitis
  • Other viral hepatitis viruses may exist but their relation to the disease is not firmly established like the previous ones (hepatitis F, GB virus C, hepatitis X)

Other infectious diseases

  • Hepatitis:
    • cytomegalovirus infection
    • herpesviral: herpes simplex infection
  • Toxoplasmosis
  • Hepatosplenic schistosomiasis
  • Portal hypertension in schistosomiasis
  • Liver disease in syphilis
  • Epstein–Barr virus infection
  • yellow fever virus infection
  • rubella virus infection
  • leptospirosis
  • Echinococcosis
  • Amoebiasis

Other inflammatory diseases

  • liver abscess
  • autoimmune hepatitis
  • primary biliary cholangitis (primary biliary cirrhosis)
  • phlebitis of the portal vein
  • granulomatous hepatitis
    • berylliosis
    • sarcoidosis
  • nonalcoholic steatohepatitis (NASH)

Alcohol

This may cause fatty liver, hepatitis, fibrosis and sclerosis leading to cirrhosis and finally liver failure.

Toxins

This includes mostly drug-induced hepatotoxicity, (DILI) which may generate many different patterns over liver disease, including

  • cholestasis
  • necrosis
  • acute hepatitis and chronic hepatitis of different forms,
  • cirrhosis
  • Effects of Acetaminophen (Tylenol)
  • other rare disorders like focal nodular hyperplasia, Hepatic fibrosis, peliosis hepatis and veno-occlusive disease.

Liver damage is part of Reye syndrome.

Tumours

Malignant neoplasm of liver and intrahepatic bile ducts. The most frequent forms are metastatic malignant neoplasm of liver)

  • liver cell carcinoma
    • hepatocellular carcinoma
    • hepatoma
  • cholangiocarcinoma
  • hepatoblastoma
  • angiosarcoma of liver
  • Kupffer cell sarcoma
  • other sarcomas of liver

Benign neoplasm of liver include hepatic hemangiomas, hepatic adenomas, and focal nodular hyperplasia (FNH).

End-stage liver disease

Chronic liver diseases like chronic hepatitis, chronic alcohol abuse or chronic toxic liver disease may cause

  • liver failure and hepatorenal syndrome
  • fibrosis and cirrhosis of liver

Cirrhosis may also occur in primary biliary cirrhosis. Rarely, cirrhosis is congenital.

Metabolic diseases

  • metabolic diseases (chapter E in ICD-10)
    • haemochromatosis
    • Wilson's disease
    • Gilbert's syndrome
    • Crigler–Najjar syndrome
    • Dubin–Johnson syndrome
    • Rotor syndrome

Vascular disorders

  • chronic passive congestion of liver
  • central haemorrhagic necrosis of liver
  • infarction of liver
  • peliosis hepatis
  • veno-occlusive disease
  • portal hypertension
  • Budd–Chiari syndrome

Cysts

  • Congenital cystic disease of the liver
  • Cysts caused by Echinococcus
  • Polycystic liver disease

Others

Amyloid degeneration of liver

Gallbladder and biliary tract diseases

  • malignant neoplasm of the gallbladder
  • malignant neoplasm of other parts of biliary tract
    • extrahepatic bile duct
    • ampulla of Vater
  • cholelithiasis
  • cholecystitis
  • others (excluding postcholecystectomy syndrome), but including
    • other obstructions of the gallbladder (like strictures)
    • hydrops, perforation, fistula
    • cholesterolosis
    • biliary dyskinesia
  • ICD-10 code K83: other diseases of the biliary tract:
    • cholangitis (including ascending cholangitis and primary sclerosing cholangitis)
    • obstruction, perforation, fistula of biliary tract (bile duct)
    • spasm of sphincter of Oddi
    • biliary cyst
    • biliary atresia

References

ICD-10 codes K70-K77: Liver Diseases [1]