Osteoid Osteoma Watchlist (log in to enable) Retrieved 2019-09-22 Source Omim Trials — Genes FOS, RUNX2, FOSB, H3-3A, H3-3B, COX2, PTGS2, USP6, SMUG1, MTCO2P12 Drugs — Interested in hearing about new therapies? Registered! Kaye and Arnold (1977) observed almost simultaneous onset of symptoms of osteoid osteoma in 2 brothers, aged 17 and 12 years. A viral or other etiology was suggested.