Cholesteatoma
Watchlist
Retrieved
2022-04-26
Source
Trials
—
Genes
SIX1,
EYA1,
EHMT1,
IL1B,
MIR21,
EGF,
TNF,
TP53,
FGF7,
MYC,
IL1A,
EGFR,
FGF2,
FN1,
HMGB1,
MAPK1,
KRT16,
ATXN3,
DEFB4A,
PCNA,
MAPK3,
TLR2,
TGFB1,
TFPI,
MMP9,
HGF,
DEFB1,
CTSD,
DEFB4B,
BMP2
SIX1,
EYA1,
EHMT1,
IL1B,
MIR21,
EGF,
TNF,
TP53,
FGF7,
MYC,
IL1A,
EGFR,
FGF2,
FN1,
HMGB1,
MAPK1,
KRT16,
ATXN3,
DEFB4A,
PCNA,
MAPK3,
TLR2,
TGFB1,
TFPI,
MMP9,
HGF,
DEFB1,
CTSD,
DEFB4B,
BMP2,
CAMP,
CLEC4D,
STAT3,
CTSL,
NOD2,
STAT5B,
LY75-CD302,
GRAP2,
TGM5,
CLDN1,
MIR106B,
BECN1,
AIMP2,
VTN,
VEGFA,
MIR16-1,
STAT5A,
NOD1,
TLR4,
DEFB103A,
TIMP1,
MIR451A,
TGFA,
DEFB103B,
MIR203A,
CLEC4A,
PYCARD,
POLDIP2,
CLEC7A,
TRPV6,
SESN2,
ABCC11,
OSTF1,
SSRP1,
CLEC6A,
MARVELD2,
TRPV3,
RNF19A,
CLEC12B,
CLEC5A,
ZHX2,
CLEC4C,
MGLL,
SPIN1,
CCL27,
GJB6,
TRPV4,
AHSA1,
CLEC10A,
A1BG,
SPRR2A,
CDSN,
EREG,
ERBB4,
ERBB2,
HBEGF,
ATN1,
CTSK,
CTSH,
CTNNB1,
MAPK14,
CRK,
CLDN3,
CDKN1A,
CXCL8,
CASP8,
CASP3,
CASP1,
BMP6,
BMP4,
BMI1,
STS,
AREG,
FAS,
ANGPT2,
AKT1,
GJB2,
IVL,
SPP1,
PIK3CA,
SLPI,
S100A7,
S100A1,
RAF1,
PTN,
PTGS2,
PSMD10,
ABCA4,
PIK3CG,
PIK3CD,
PIK3CB,
PGF,
JAK1,
NOS2,
NOS1,
NME1,
COX2,
MRC1,
MMP2,
LY75,
LOX,
LCN2,
KRT19,
KRT13,
MTCO2P12
Drugs
—
Registered!
Cholesteatoma is an abnormal growth of skin in the middle ear behind the eardrum. It can be congenital (present from birth), but it more commonly occurs as a complication of chronic ear infections. Individuals with this condition usually experience a painless discharge from the ear. Hearing loss, dizziness, and facial muscle paralysis are rare but can result from continued cholesteatoma growth. Treatment usually involves surgery to remove the growth.