Laurence-Moon Syndrome Watchlist (log in to enable) Retrieved 2021-01-23 Source Orphanet Trials — Genes PNPLA6 Drugs Leuprolide acetate ( LUPRON INJECTION ) Interested in hearing about new therapies? Registered! A very rare genetic multisystemic disorder characterized by pituitary dysfunction, ataxia, peripheral neuropathy, spastic paraplegia, and chorioretinal dystrophy.