Bifid Nose, Autosomal Dominant

Clinical Features

Anyane-Yeboa et al. (1984) reported 5 women in 3 generations who had bifid nose without hypertelorism. Skull films and chromosomes of the youngest sisters were normal. Miles and Smith (1985) insisted that the dominant bifid nose syndrome is a distinct entity without ocular hypertelorism. In the family they studied, 10 persons had a bifid nasal tip. Of these, 8 had ptosis and 2 scoliosis. Of 3 males, 2 had cryptorchidism.

Inheritance

Anyane-Yeboa et al. (1984) stated that the bifid nose in this family was most likely an autosomal dominant trait. A recessive form (210400) may exist.