Situs Inversus
Watchlist
Retrieved
2022-04-26
Source
Trials
—
Genes
CFAP53,
NODAL,
PKD1L1,
DNAH9,
CITED2,
ACVR2B,
NME7,
MMP21,
ANKS3,
CFAP52,
ANKS6,
ZIC3,
NPHP3,
CFC1,
ACTG2,
LETM1,
NSD2,
NPHP3-ACAD11,
NELFA,
DNAH7,
TNF,
CCR5,
ITIH4,
HLA-C,
IFNA1,
PTPN11,
IFNA13,
IVNS1ABP,
INVS,
DNAH11
CFAP53,
NODAL,
PKD1L1,
DNAH9,
CITED2,
ACVR2B,
NME7,
MMP21,
ANKS3,
CFAP52,
ANKS6,
ZIC3,
NPHP3,
CFC1,
ACTG2,
LETM1,
NSD2,
NPHP3-ACAD11,
NELFA,
DNAH7,
TNF,
CCR5,
ITIH4,
HLA-C,
IFNA1,
PTPN11,
IFNA13,
IVNS1ABP,
INVS,
DNAH11,
IL7,
IL15,
CXCR6,
MNS1,
CXCL10,
TBX1,
IFNB1,
CCDC151,
WAS,
TRBV20OR9-2,
IL10,
CXCR4,
HLA-B,
IFITM3,
DNM1L,
CCL4L2,
TNFSF13B,
CH25H,
PDLIM7,
SIRT1,
LRRC6,
SH3BP4,
ARTN,
SDS,
ACTB,
DNAI1,
IL37,
CD24,
CALHM6,
EIF2AK4,
MIR212,
MIR206,
MIR150,
MIR130A,
CCL4L1,
DNAAF3,
RSPH9,
ENKUR,
PIFO,
MUC16,
TRIM5,
HAVCR2,
MAVS,
ACSS2,
ARMC4,
LZTFL1,
CDON,
IL21R,
CD274,
SESN1,
RIPK1,
SPP1,
KMO,
MADCAM1,
IFN1@,
HNF4A,
GZMB,
GDF1,
GCK,
FOXJ1,
FCGR3B,
FCGR3A,
F3,
DPP4,
CDO1,
CD58,
CD80,
CD28,
CD4,
CD247,
CASP1,
CXCR5,
BCL6,
BCL2,
ATF4,
APP,
ANXA5,
NR0B1,
AGRP,
IFNAR2,
IL1B,
IL2,
PKD2,
ZFP36,
TLR4,
SP1,
SIGLEC1,
SHH,
CCL5,
CCL4,
CCL3,
PRKCSH,
PPARA,
PMP22,
OPRM1,
IL6,
NPR2,
MRC1,
MPZ,
MPL,
LTB,
KLRC2,
KLRC1,
KIR2DL4,
IRAK1,
IL18,
IL17A,
LINC02605
Drugs
—
Registered!
Situs inversus is a condition in which the arrangement of the internal organs is a mirror image of normal anatomy. It can occur alone (isolated, with no other abnormalities or conditions) or it can occur as part of a syndrome with various other defects. Congenital heart defects are present in about 5-10% of affected people. The underlying cause and genetics of situs inversus are complex. Familial cases have been reported.