Autoimmune Hepatitis
Watchlist
Retrieved
2021-01-23
Source
Trials
—
Genes
IL10,
IFNG,
IL4,
IL2,
IL6,
IL5,
IL13,
IL22,
TGFB1,
CXCL1,
IL9,
ALDOB,
IL18,
LEP,
CCL2,
CCL5,
C1S,
PDIA3,
HLA-DQB1,
SH2B3,
HLA-DQA1,
TNF,
HLA-DQA2,
HLA-DRB1,
CYP2D6,
ATXN2,
RBM45,
CTLA4,
SEPSECS,
GPT
IL10,
IFNG,
IL4,
IL2,
IL6,
IL5,
IL13,
IL22,
TGFB1,
CXCL1,
IL9,
ALDOB,
IL18,
LEP,
CCL2,
CCL5,
C1S,
PDIA3,
HLA-DQB1,
SH2B3,
HLA-DQA1,
TNF,
HLA-DQA2,
HLA-DRB1,
CYP2D6,
ATXN2,
RBM45,
CTLA4,
SEPSECS,
GPT,
AMELX,
FOXP3,
IL2RA,
ISG20,
PSC,
HLA-DPB1,
AIRE,
VDR,
PDCD1,
FTCD,
IL1B,
HLA-DRB3,
HLA-A,
ENAM,
TPMT,
ACTB,
HLA-DOA,
GSTT1,
HLA-DRB4,
CYP1A2,
LOC107987479,
HPGDS,
PPIG,
PTPN22,
CD28,
IL17A,
LGALS3BP,
TRIM21,
MIR223,
IFNB1,
LGALS9,
CXCR1,
KIR3DL1,
TBX21,
CXCL10,
MLKL,
CD274,
HAVCR2,
HAMP,
RETN,
IL1RN,
MIF,
CYP2D7,
HLA-B,
FH,
GATA3,
GEM,
FAS,
ALB,
DLAT,
HLA-C,
CYP2B6,
ICOS,
IL37,
IL17C,
CD74,
CD40LG,
CARD10,
ABCC4,
SLC17A5,
NOX4,
CD1D,
CASP1,
C4A,
GOLM1,
KRT20,
MS4A1,
CHRNA4,
CRP,
SMUG1,
MPRIP,
NUDT15,
KLRK1,
ABCC2,
RIPK3,
BTG3,
CCR7,
FGL2,
CCR3,
TNFSF13B,
TNIP1,
IFNA1,
ASPH,
RNPC3,
FASLG,
ADA,
KLRC4-KLRK1,
CD24,
SYCE1L,
TEC,
MIR155,
MIR143,
C6orf120,
GSTK1,
PGAM5,
IL34,
KLF14,
SLCO6A1,
IL17RE,
FCRL3,
WDR11,
NLRP3,
IL33,
ARG1,
JAM3,
PDCD1LG2,
TNFAIP8L2,
IL25,
HHIP,
KLHL12,
IL21,
ARSA,
KLHL1,
TNFRSF14,
MYDGF,
MSC,
UMOD,
OGT,
GABPA,
CD200,
MMP1,
DNASE1,
ATN1,
FBL,
FANCC,
KRT18,
KRT8,
FCGR2A,
KIR2DS1,
FCGR2B,
INPP5D,
INS,
IDO1,
GATA2,
CDR3,
GCG,
GLI2,
CXCL8,
IL7R,
GPR39,
NR3C1,
IL4R,
GSTM1,
GSTM2,
HK1,
IL1A,
HRAS,
HSPD1,
IFNA13,
NFE2L2,
NOS2,
OCA2,
OPRD1,
YY1,
IFNA2,
TSHR,
TRAF6,
NR2C2,
TPO,
CYP2C19,
TNFAIP3,
CYP2C9,
TLR3,
TLR2,
TG,
TRBV20OR9-2,
MAP3K7,
STXBP2,
STAT4,
CYP2E1,
SLC2A3,
CXCL12,
CYP3A4,
DBT,
DCK,
S100B,
S100A1,
RPS20,
RORC,
PTPRC,
POMC,
PDC,
ACTA1
Drugs
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Registered!
A rare hepatic disease characterized by immune-mediated, acute or chronic liver inflammation, clinically presenting as cryptogenic hepatitis, with interface hepatitis on histological examination, elevated serum aminotransferase levels, and hypergammaglobulinemia, in the presence or absence of specific circulating autoantibodies. Patients may be asymptomatic, chronically ill, or present with acute liver failure. All ages and both genders may be affected, although there is a clear female preponderance. Concurrent autoimmune diseases are frequently observed.