Dyschromatosis Symmetrica Hereditaria
A rare genodermatosis characterised by the presence of hyperpigmented and hypopigmented macules, principally located on the extremities and limbs.
Clinical description
The first manifestations of the disease generally appear during early childhood.
Etiology
A mutation has been identified in the double-stranded RNA-specific adenosine deaminase (ADAR) gene.
Genetic counseling
Transmission is autosomal dominant.