Oculocerebral Hypopigmentation Syndrome Of Preus

Preus et al. (1983) described 2 sibs, born of consanguineous Italian parents, who had an oculocerebral hypopigmentation syndrome consisting of growth retardation, dolichocephaly, cataracts, highly arched palate, small and widely spaced teeth, generalized hypopigmentation, psychomotor retardation, and hypochromic anemia. Patton et al. (1987) concluded that this syndrome was distinct from the oculocerebral hypopigmentation syndrome described by Cross et al. (1967); see 257800.