T-Cell Leukemia
Watchlist
Retrieved
2021-01-18
Source
Trials
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Genes
NOTCH1,
LMO2,
STAT3,
PTPN2,
LMO1,
HMGA1,
TLX1,
TCL1B,
CDKN2A,
TP53,
THBS1,
TRBV20OR9-2,
CNTN2,
ATF7IP,
HBZ,
TCL1A,
IL2RA,
IL2,
FAS,
ISG20,
TAL1,
FOXP3,
MYC,
PTHLH,
TXN,
CCR4,
AKT1,
IL1B,
SOAT1,
IRF4
NOTCH1,
LMO2,
STAT3,
PTPN2,
LMO1,
HMGA1,
TLX1,
TCL1B,
CDKN2A,
TP53,
THBS1,
TRBV20OR9-2,
CNTN2,
ATF7IP,
HBZ,
TCL1A,
IL2RA,
IL2,
FAS,
ISG20,
TAL1,
FOXP3,
MYC,
PTHLH,
TXN,
CCR4,
AKT1,
IL1B,
SOAT1,
IRF4,
ICAM1,
CADM1,
IL4,
LCK,
CDKN2B,
IL1A,
HLA-A,
ETV6,
CD38,
RELA,
SYT1,
H3P10,
IL15,
MVP,
GORASP1,
WNK1,
TMEM132D,
ERVK-20,
ERVW-1,
ERVK-18,
ERVK-32,
BCR,
PTEN,
FCGRT,
PSMB6,
PIK3CD,
PIK3CB,
PIK3CA,
ATM,
MTCP1,
MTAP,
MSH3,
HSP90AA1,
IL10,
PTPRA,
IFNA1,
IFNA13,
LRP1,
RPSA,
IL2RG,
KMT2A,
PIK3CG,
TCL6,
DLL1,
STAT1,
TRBC1,
YY1,
TGFB1,
CYP19A1,
SUB1,
SH2D1A,
TNFRSF4,
TERF2,
TRG,
LYL1,
CCR9,
BCL11B,
MRPL28,
GLIS2,
TBPL1,
CIB1,
MMP9,
VCAM1,
VEGFA,
LBR,
H3P9,
KRT7,
JAK2,
ITGB2,
ITGAL,
CXCR4,
H3P13,
TPPP,
REG1A,
TRB,
TRBV7-9,
RAF1,
NXT1,
S100B,
SATB1,
SCLY,
PTH,
SELL,
MAPK1,
PTPA,
PLEK,
SOCS1,
PIM1,
TCF3,
TRBV16,
IL23A,
ABCB1,
NOTCH3,
KRT20,
TET2,
NFKB1,
FBXW7,
ATL2,
MYB,
RAG2,
CDR3,
RPL10,
IL2RB,
ATN1,
MSH6,
CREB1,
FUT4,
CD52,
CDKN2D,
CDKN1B,
CYLD,
IFNG,
IGH,
RUNX1,
MS4A1,
HES1,
GZMM,
CEBPE,
EZH2,
IL9,
BCL2,
CD44,
CD34,
F9,
SERPINH1,
CUX1,
DICER1,
AUTS2,
TBC1D9,
FBXO7,
SIRT1,
NOMO1,
ATL3,
SLC44A1,
POT1,
RNF19A,
IL15RA,
PTPN22,
POLDIP2,
IFT172,
TINF2,
SIGLEC7,
SND1,
IGHV3OR16-7,
IGHV3-69-1,
CAV1,
CASP9,
CASP8,
TRBC2,
CASP3,
TRAV29DV5,
TRAJ60,
TRAC,
TPX2,
CCNB1,
SACM1L,
LONP1,
HIPK3,
SPATA2,
SART3,
HERPUD1,
CD86,
TNFRSF8,
GRAP2,
IL32,
CILK1,
MAGI1,
LPAR2,
CBFA2T2,
BCL10,
LDB1,
CDK5R1,
KAT2B,
RASGRP1,
PIAS3,
PRMT5,
CD9,
IKZF2,
CHP1,
POLG2,
PSIP1,
TLX3,
TMED2,
CCND2,
CD3D,
CTCF,
CXCR6,
LBX1,
TXNIP,
AHSA1,
CD247,
PROCR,
TSPO,
NCKIPSD,
BRS3,
CD209,
TARP,
ZFAS1,
PIM3,
MIR31,
MIR155,
MIR146A,
MIR126,
MIR106A,
LOC390714,
TBPL2,
H3P44,
NRK,
CADM4,
PTCRA,
CNKSR3,
PDIK1L,
NRSN1,
JPX,
MIR20B,
POTEF,
LOC102724971,
H3P5,
H3P19,
ADRA2B,
JAG1,
LINC02605,
AHR,
LOC105379528,
LOC102723407,
CDKN2B-AS1,
AMFR,
APEX1,
RAB4B-EGLN2,
RPL17-C18orf32,
MIR1193,
ALL1,
CMC4,
TAF8,
BIRC2,
RASGRP4,
AHI1,
POLE4,
CCL28,
TDP1,
BAK1,
VAC14,
BAX,
GIN1,
CCND1,
SLC12A9,
TMED9,
BCL2A1,
BCL2L1,
NRP1,
UBR5,
BMP6,
SPOCK3,
TM9SF3,
ACKR3,
EGLN2,
BIRC5,
MYADM,
LRSAM1,
BIRC3,
ASCC2,
USP44,
NOX5,
XIAP,
DEPTOR,
ZMIZ1,
FASLG,
ATF3,
UBL5,
KMT2C,
POLD4,
NDRG2,
AICDA,
HCAR3,
CD40LG,
ADAM21,
NFKB2,
NRAS,
PNP,
HGF,
NPY,
HLA-B,
NOS2,
NOS1,
HLA-DOA,
TNFSF10,
NFE2L1,
NCAM1,
HNRNPA1,
TLX2,
MUC1,
HOXA9,
HPR,
NRF1,
OAS3,
P4HB,
PBX1,
FCGR3A,
FCGR3B,
PSMD12,
FOXE3,
MAP2K7,
MAPK3,
FOS,
FOSL2,
PMS1,
MTOR,
PIN1,
GLS,
GPR42,
HCLS1,
PDCD1,
HRES1,
MSH2,
ABCC1,
LGALS9,
LCN2,
IL3,
IL4R,
LAIR1,
IL5,
KRAS,
JUND,
JUN,
JARID2,
JAK3,
IL6,
ITK,
ITGB7,
IL7,
ITGB1,
LGALS1,
LIF,
MRC1,
IKBKB,
MPP1,
MMP7,
MMP2,
IRF8,
MLH1,
MIP,
MET,
MEF2C,
MDM4,
ADAM11,
MCM2,
MCL1,
IFNB1,
LYN,
IGFBP7,
PTPN6,
ERG,
PVT1,
TYR,
TNFRSF1B,
TNFRSF1A,
TNF,
TMSB4X,
COMT,
TERT,
TERF1,
TCTA,
TRGC1,
CRK,
CRP,
MAPK14,
TRA,
TCL4,
ZEB1,
TXNRD1,
TYROBP,
TAT,
KDM6A,
PTCH2,
KHSRP,
PIK3R3,
RANBP3,
FOXN1,
NR0B2,
ZNF282,
IL13,
AIMP2,
USP7,
CD151,
CDC20,
VHL,
CDK2,
CDKN1A,
CTNNB1,
TARS1,
RAC1,
CCL2,
EDNRA,
SAI1,
EGR1,
S100A4,
S100A1,
RPS6KA3,
RPL17,
ADRA1A,
RNASE3,
RGS1,
EIF4E,
EIF4G1,
ELF2,
EPHB2,
RAD51,
CCL1,
CCL3,
TALDO1,
CCL22,
DNMT3A,
SYK,
STAT5B,
STAT5A,
DNTT,
DPP4,
SSTR4,
SPTAN1,
FSCN1,
SNCA,
SNAP25,
SMARCA4,
PMEL,
SHB,
E2F4,
ACTB
Drugs
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Registered!
T-cell leukemia describes several different types of lymphoid leukemia which affect T cells.
Types include:
- Large granular lymphocytic leukemia
- Adult T-cell leukemia/lymphoma
- T-cell prolymphocytic leukemia
In practice, it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and they are often grouped together.