Obesity-Hypoventilation Syndrome Watchlist (log in to enable) Retrieved 2019-09-22 Source Omim Trials — Genes CENPJ, COPD Drugs — Interested in hearing about new therapies? Registered! Falsetti et al. (1964) described brother and sister with a syndrome characterized by obesity, cyanosis, somnolence, muscular twitching, and periodic breathing. See 164160 for a discussion of the genetics of obesity.