Sonoda Syndrome

Clinical Features

Among the children of presumably unrelated parents who, however, came from lines that had been located in a rather small town for a long time, Sonoda et al. (1988) described 2 boys and a girl with a syndrome of congenital heart disease, round face with depressed nasal bridge, small mouth, short stature, developmental retardation, relatively dark skin, and high axial triradius in the dermatoglyphic analysis. Pulmonary valvular stenosis was diagnosed in 1 of the children; in a second, ventricular septal defect, which was thought to have closed spontaneously, was diagnosed, and the same lesion may have been present in the third child.