Chronic Lymphocytic Leukemia
Watchlist
Retrieved
2022-04-26
Source
Trials
—
Genes
TP53,
PLCG2,
ATM,
POT1,
IGHV3-21,
P2RX7,
LEF1,
SF3B1,
BCL2,
IRF4,
BRAF,
XPO1,
SP140,
BMF,
PRKD2,
ACOXL,
FARP2,
SYK,
BTK,
QPCT,
IL6,
BIRC3,
CCND1,
C11orf21,
MYC,
CD5,
ITGA4,
BCL6,
PIK3CA,
RPS15
TP53,
PLCG2,
ATM,
POT1,
IGHV3-21,
P2RX7,
LEF1,
SF3B1,
BCL2,
IRF4,
BRAF,
XPO1,
SP140,
BMF,
PRKD2,
ACOXL,
FARP2,
SYK,
BTK,
QPCT,
IL6,
BIRC3,
CCND1,
C11orf21,
MYC,
CD5,
ITGA4,
BCL6,
PIK3CA,
RPS15,
PMAIP1,
MTHFR,
IKZF3,
TNFRSF11A,
TFRC,
PTGS2,
TNFSF11,
ARL11,
MIR143,
U2AF1,
VDR,
LILRA4,
PPP2R5C,
SRSF2,
CDKN2B-AS1,
ZRSR2,
MIR145,
RBL2,
IL19,
KLRC4,
POLB,
IGHG1,
CPEB1,
NFKBIE,
TOPBP1,
BCL2L11,
DLEU1,
FAS,
CASP8,
HLA-DRB1,
NRAS,
KRAS,
SAMHD1,
FBXW7,
CFLAR,
BAK1,
CASP10,
HRAS,
IRF8,
IL22,
NCAPH2,
CD274,
JAK2,
MDM2,
MIR16-1,
MIR21,
CXCL12,
RPS6KB1,
IL21,
MGAT5,
RREB1,
DTNB,
RHOU,
RFX7,
MCL1,
HSP90AA1,
MIR4435-2HG,
IGHV3-69-1,
GGNBP1,
VMP1,
IGHV3-52,
CSRNP1,
CCR7,
LPL,
IGHV1-69,
CLPTM1L,
LPP,
IFIH1,
HLA-DQA2,
SPG7,
MIR34A,
CTNNB1,
CXADR,
HDLBP,
MIR15A,
CIB3,
PVT1,
MIR155,
NOTCH1,
TLR9,
MYNN,
ILRUN,
ROR1,
KRT20,
OAS3,
FAM126B,
FCER2,
PIK3CG,
PIK3CD,
PIK3CB,
OPRM1,
SERPINB6,
ABCB1,
MDS2,
LAIR1,
ULK4,
CD52,
PPIL3,
GRAMD1B,
LRRC34,
MMP9,
RNASEH2B,
AICDA,
BANK1,
PTPN11,
CD200,
EPHB2,
MAPK1,
GPR37,
MYD88,
FKRP,
PRKAR1A,
ACOXL-AS1,
NCK1,
LOC390714,
RTEL1,
DRAIC,
STAT3,
HLA-DQA1,
IBTK,
CASP3,
IL4,
BAX,
CXADRP1,
TREX1,
CD34,
ATR,
TSBP1-AS1,
LOC102724971,
IL10,
CD38,
ARR3,
VEGFA,
CD40,
CD40LG,
CASC19,
IGH,
PCAT1,
BCL3,
MS4A1,
ELL2,
CASR,
TNF,
TNFSF13,
CDR3,
CXCL8,
TCL1A,
CLLS2,
DACT3-AS1,
IPCEF1,
DLEU2,
TBC1D9,
BCR,
CXCR4,
ZAP70,
CD19,
TCL1B,
LOC102723407,
IL2,
CDKN2A,
ADAR,
CLLU1,
TRIM13,
ACTA2,
IGHV3OR16-7,
SF3B2,
AKT1,
TNFSF13B,
LOC105379528,
NR1I3,
TSBP1,
SP110,
RNASEH2A,
RNASEH2C,
CD79B,
IFNG,
PTPRC,
WNT5A,
TNFSF10,
TRBV20OR9-2,
NOTCH2,
XIAP,
FCMR,
TNFRSF17,
MIR150,
BCL11B,
PTEN,
FCGR3A,
MME,
HTC2,
DAPK1,
IGHV4-34,
CD1D,
BRCA2,
CDKN1B,
SLC35B2,
GDE1,
NFKB1,
FGF2,
PAX5,
SLC7A4,
SELL,
B2M,
ICAM1,
RB1,
IGLV3-21,
ATN1,
CD28,
CR2,
PARP1,
PDE4A,
ANP32B,
IL1B,
HLA-G,
EZH2,
CXCR5,
ANGPT2,
HIF1A,
BCL11A,
NFATC1,
ABL1,
IL2RA,
IGHV4-39,
ISG20,
CDKN2B,
MAPK3,
CTLA4,
CSF2,
ABCC1,
CD22,
CD80,
PDCD1,
PDLIM7,
FMOD,
MAPK14,
SUB1,
MIR223,
ABCB4,
NT5E,
MIR34B,
CYP3A4,
CD44,
NOS2,
MIR29C,
WLS,
MIR29B2,
TNFRSF10A,
PTPA,
BMS1P20,
FANCB,
CIB1,
MARCKSL1,
TERT,
IL17A,
CDKN1A,
TP73,
APAF1,
STAT6,
CXCR3,
CD58,
MRPL28,
HLA-A,
TLR2,
RBM45,
CDK4,
AHSA1,
ARHGAP24,
STAT1,
CD69,
CD79A,
HDAC1,
IL15,
HCLS1,
CRK,
NXT1,
CD74,
H3P9,
MIR17HG,
RNF19A,
GLI1,
POLDIP2,
CD8B,
DEL13Q14,
CD8A,
AIMP2,
PIM1,
BID,
EGFR,
CD27,
PTPRO,
CTTN,
MAP2K1,
CCND2,
PRKCB,
ERCC1,
MIR29B1,
CD14,
PDE3B,
FOXP1,
CCL28,
GRAP2,
CASP9,
ITGAL,
IL1A,
SDC1,
IGL,
CCL4,
CCL3,
CD86,
SERPINA5,
ITGB1,
IL4R,
MUL1,
ITGB2,
IL9,
LCK,
FCRL2,
LGALS1,
ITGAX,
SMYD3,
LGALS3,
VIM,
STAT5A,
STAT5B,
IGKV3-20,
IGHV1-2,
TK1,
IGHV5-78,
UGT2B17,
VAV1,
VCAM1,
PDE7B,
TP63,
MBL2,
PRAME,
ARHGEF7,
BCL10,
IKZF2,
ABCG2,
CD160,
HDAC9,
DCTN6,
ZNRD2,
CXCL13,
SOX11,
SETD2,
SLC2A1,
SLAMF1,
MFAP1,
MKI67,
NPM1,
RCBTB1,
PRKN,
PCNA,
PDE7A,
PLAT,
PPARA,
PRKCA,
PSMD9,
RAC1,
ZBTB7A,
TLR7,
TMED7,
RELA,
MBL3P,
IL21R,
CCL19,
ICOS,
SFRP4,
SFRP1,
COLEC10,
CFH,
TMED7-TICAM2,
CRY1,
NR3C1,
FCGR3B,
CDK9,
FCGR2A,
HGF,
CSF3,
ANPEP,
ANXA5,
HSPA4,
CDH1,
IGLV@,
HLA-DRB4,
HMMR,
CAV1,
BCL2A1,
MIR221,
BIRC2,
ETV6,
ERCC2,
CD37,
APRT,
TICAM2,
PDIK1L,
CDKN3,
E2F1,
CREBRF,
IGKV@,
CD6,
H3P10,
CLEC12A,
S1PR1,
IGLL5,
IGHD,
IGF1R,
COL11A2,
H3P23,
CBLL2,
PRDM1,
ENTPD1,
DUSP8,
IFI27,
TNFRSF13C,
JAG1,
FOXO3,
MAP2K7,
NRIP1,
PTPN22,
EDNRA,
PTPN6,
MIR650,
ERBB2,
CD1C,
TRIM33,
DEK,
EIF4E,
CD2,
HMGA2,
MIR132,
PTK2,
EPO,
CD247,
CLEC4D,
RUNX1,
GSTK1,
BRCA1,
TNFRSF13B,
PAWR,
DLEU7,
THPO,
SMUG1,
MBTPS1,
BECN1,
TET2,
SOCS1,
FH,
FGFR3,
BTG4,
FCGR2B,
FCGR1A,
DUX4,
PIK3R2,
PLAG1,
CALR,
KCNRG,
RAD51,
NR0B2,
TERF2IP,
F2R,
PON1,
POU2AF1,
SHC3,
ETV5,
PPP2R1B,
EDN1,
H3P40,
USP7,
STK11,
CYLD,
DROSHA,
IGKV1-5,
TRPC1,
MIR34C,
CDK2,
TRAF2,
IGKV1-39,
ST13,
IGKV2-29,
MIAT,
IGKV2-30,
TNFAIP3,
CDR1,
CDR2,
SKP2,
TLR4,
SYT1,
TAP2,
CHD2,
IGHD3-3,
TCF3,
KLF6,
TRG,
TERC,
TERF1,
IGHV3-11,
CCR6,
TGFB1,
IGHV3-23,
HPGDS,
CD55,
RAG2,
DPP4,
IRAK4,
GAL,
ZFP36,
ASCC1,
REL,
DUSP5,
XRCC1,
RNH1,
SIRT1,
ROS1,
IGK,
RPE65,
TNFSF8,
DSP,
DOK1,
DBH,
WNT3,
SCT,
MIR19B1,
CD47,
DNMT1,
CCL21,
MIR203A,
CD59,
DDX3X,
SEMG1,
SET,
SFRP2,
UVRAG,
SFRP5,
BMI1,
BTG1,
LTA,
WNK1,
LAG3,
RAPH1,
SLC29A2,
HNF4A,
LBR,
NR4A1,
HLA-DQB1,
PRRT2,
GORASP1,
LIG4,
FASLG,
COP1,
MIR155HG,
BAG3,
G6PD,
CD180,
LYN,
SLC28A3,
ERICD,
WIF1,
ASS1,
FCRL1,
FCRL3,
MDM4,
GZMB,
MET,
ATF5,
CD83,
ARHGAP20,
DNER,
IRAIN,
GSTM1,
ADAM29,
CARD11,
IL2RB,
IL3,
ACP3,
ACTB,
IL6R,
IL7,
SEMA4D,
BCL2L12,
HAVCR2,
TNFRSF9,
ORAI1,
PPP1R13L,
LILRB1,
INSR,
DNM1L,
HSPD1,
CKAP4,
HSF1,
APC,
MED12,
LILRB4,
RTL10,
IL24,
JAK3,
JUN,
PIM2,
KDR,
MTDH,
MIB1,
THBS1,
PER2,
ACSBG1,
BCL2L1,
TIGAR,
SLCO6A1,
GNAS,
MYCN,
BCL9,
MPO,
PEG10,
ARHGEF2,
MXI1,
NOS3,
SOCS3,
KLHL7,
BLK,
GPRC5A,
GDF1,
MYH2,
CD84,
NRP1,
DICER1,
MMP2,
MGA,
BTLA,
KLRC4-KLRK1,
NOS1,
KLRK1,
ZNF331,
MLH1,
ST13P4,
GAB1,
WWC1,
LPAR3,
DAPK2,
IGHV5-51,
KIR2DL5B,
MTCO2P12,
ADAM28,
MALT1,
RN7SL263P,
MCAT,
NTSR2,
RABGEF1,
LDOC1,
CYSLTR1,
LRIG1,
ZMYND11,
H3P8,
DMRT2,
IGHV3-30,
LINC01672,
H3P31,
IGHV3-41,
MIR196B,
BRD4,
IGHV3-75,
LINC01541,
TARP,
RNASE12,
MAPK8IP2,
PPP1R13B,
CXCR6,
CTCF,
MRD4,
CD226,
MIR377,
RNA28S5,
RNA28SN4,
PLK2,
IGHV4-59,
IGHV4-38-2,
MIR3151,
RAI1,
MIR20B,
DUSP5P1,
RBM14-RBM4,
NCOA6,
KANK2,
CNOT1,
PSIP1,
DKK1,
SIGLEC7,
FOXD3,
TP53COR1,
CHEK2,
TRERNA1,
PHB2,
RNA28SN5,
LINC-ROR,
CYFIP2,
CCR2,
MYEOV,
MLSM7,
AATF,
SIRT2,
ATF6,
TINF2,
MLXIP,
SPANXA2,
MIR640,
SND1,
CDC37,
RPP14,
PDCD4,
DKK3,
RIPK3,
SH3BP4,
CERNA3,
MAGED4,
PHLPP1,
MIR146B,
MIR1206,
LPIN1,
MPRIP,
SLC7A9,
BBC3,
CACYBP,
B3GAT1,
MIR202,
MIR484,
LAMP3,
GATA6-AS1,
COMMD3-BMI1,
TNRC6B,
MIR708,
SIRT3,
ING5,
MIR339,
SUGP1,
GOPC,
GPR151,
SPRYD7,
KIR2DL5A,
TSACC,
TMEM132D,
NDRG2,
TMCC3,
TWIST2,
MRGPRX4,
DOCK11,
MRGPRX3,
ACE2,
SIGIRR,
SENP2,
SLAMF6,
LGR6,
BACH2,
HPSE2,
CPAT1,
CYSLTR2,
E2F7,
CRYGEP,
ALLC,
ASXL1,
OXER1,
HFM1,
NOP10,
BMP2K,
DOCK10,
WDR11,
RNF217,
ADCY10,
SHISA3,
TWSG1,
CCDC50,
NXF2,
SLC2A4RG,
APCDD1,
TCIM,
DUSP22,
SMYD2,
PRIMA1,
ACKR3,
GALNT11,
CRLF2,
NOD2,
ITCH,
RITA1,
MAGED4B,
ATAD1,
FCRL5,
FCRL4,
DOHH,
PARP9,
FERMT3,
FCRLA,
C19orf48,
SIL1,
SETDB2,
KMT5C,
MRO,
TRIM63,
HDAC10,
SYVN1,
MINDY4,
HVCN1,
RPAIN,
COL18A1,
PDCD1LG2,
PPP1R2C,
PWWP3A,
NLRP3,
IL17F,
TP53INP1,
DRC1,
FRTS1,
CRB3,
PAGR1,
DERL3,
CCDC34,
MCPH1,
DPP9,
SUV39H2,
EHMT1,
IL33,
KLHL6,
STN1,
TSLP,
ABCC11,
ASRGL1,
PACC1,
TIGIT,
MIR338,
MIR196A2,
MIR26A1,
BLNK,
TMOD4,
MIR222,
MIR22,
MIR214,
MIR212,
MIR20A,
DPP7,
SH3KBP1,
MIR29A,
SPANXA1,
CXXC1,
KLK14,
CRNN,
CHST11,
MIR181B1,
MIR16-2,
AK3,
TRAT1,
MIR28,
MYLIP,
NRK,
VN1R17P,
MIR337,
IGHJ6,
IGHD3-10,
IGHD3-9,
DLL1,
MIR335,
GPR166P,
IGLV1-44,
IGLJ2,
MIR9-3,
MIR30D,
MIR92A1,
MIR9-2,
IGKJ2,
IGKJ1,
TRIB2,
LAMTOR2,
MIR9-1,
RGCC,
MCTS1,
FOXP3,
MIR15B,
KMT5B,
BCOR,
GAR1,
ABCB5,
DLL4,
UGT1A1,
HECTD4,
FBLIM1,
PPP1R12C,
NEAT1,
PGPEP1,
LAX1,
ING4,
MRGPRX1,
MARCHF1,
NCR3,
PCSK9,
GPRC6A,
MARCHF8,
MPEG1,
CEP55,
MED19,
GOLGA6A,
ARSH,
PWAR4,
CLEC17A,
MZB1,
BFAR,
MIR146A,
MIR142,
MIR130A,
WNT16,
DCDC2,
MIR126,
MIR125B1,
ISYNA1,
MIR125A,
IL23A,
HDAC7,
MIR124-1,
MIR122,
MIR107,
LINC01194,
SF3B6,
YPEL5,
MIR17,
NAT1,
GNLY,
HAS1,
GPR42,
GPS2,
GPT,
GRB2,
GRB7,
GRN,
GRM3,
GSR,
GSTM2,
GSTP1,
GSTT1,
GUSB,
H1-0,
HDAC2,
RBM14,
HDC,
NCKAP1L,
HK1,
MNX1,
HLA-DOA,
HLA-DPB1,
HNRNPL,
HOXA@,
HOXA4,
HOXA9,
HOXA13,
HOXB7,
HPX,
GPM6A,
GPLD1,
GNB3,
GLUD2,
FAU,
FCGR1B,
FOXM1,
FOXO1,
FLG,
FLI1,
FLII,
FLT1,
FLT3,
FLT3LG,
FLT4,
FN1,
FOS,
FOSB,
FRA16A,
MTOR,
FRZB,
GAST,
XRCC6,
B4GALNT1,
GALNS,
GATA2,
GDNF,
GEM,
GJA1,
GLB1,
GLUD1,
AGFG1,
HES1,
HSPA5,
IL18,
CXCL10,
INPPL1,
IRF2,
IRF3,
IRF5,
ITGAM,
ITPR1,
ITPR3,
IVL,
JAK1,
JARID2,
JUNB,
JUND,
KCNK3,
KIR2DS1,
KIR2DS3,
KIR3DL1,
KLKB1,
KRT31,
LAMA4,
LAMP1,
LAMC2,
LCP1,
LCP2,
LGALS9,
LMNB1,
LMO1,
ILK,
IL16,
HSPB1,
IL15RA,
HSPB2,
HSPG2,
ID4,
IDH1,
IDH2,
IDUA,
IFI16,
IFNA1,
IFNA13,
IFNGR1,
IFNGR2,
IGF1,
IGHG3,
IGHM,
IKBKB,
IL1RN,
IL2RG,
IL3RA,
IL5,
IL7R,
CXCR1,
CXCR2,
IL11,
IL11RA,
IL12A,
IL12RB2,
IL13,
FAT1,
FASN,
FAP,
BRS3,
BST1,
BUB1,
FMNL1,
CALCA,
CANX,
CASP2,
CASP6,
RUNX1T1,
CBFB,
CCND3,
CCNH,
CD3G,
CD9,
CD33,
SIGLEC6,
CD36,
CD53,
CD68,
CD70,
CDK1,
CDK8,
CEBPA,
CEBPB,
AKR1C4,
CHEK1,
CLCN5,
TPP1,
BSG,
BNIP3,
CCR8,
BMP1,
ABO,
ACP1,
ADA,
ADCYAP1R1,
ADRA1A,
ADRA2B,
ADRB2,
AMFR,
AMPD1,
ANG,
ANXA7,
BIRC5,
APOE,
AQP1,
RHOH,
ARNT,
ARSD,
ATP2B4,
ALDH7A1,
BAD,
BAG1,
BCHE,
BCL2L2,
OPN1SW,
BDNF,
BGN,
BIK,
CMA1,
CNR1,
PTK2B,
DXO,
DTX1,
DUSP2,
DVL1,
DVL2,
EBF1,
GPR183,
EFNA4,
EGF,
EGR1,
EGR2,
EGR3,
EIF4EBP1,
EIF4G1,
ENG,
ENO1,
EP300,
EPHA3,
EPHB6,
ERCC4,
ERN1,
ESR1,
ESR2,
ETS1,
ETV3,
MECOM,
EZH1,
F9,
DSC3,
DOCK2,
MAP3K8,
DNMT3B,
COX8A,
CPOX,
CR1,
ATF2,
CRMP1,
CRP,
CRYGC,
CSF1R,
CSF2RA,
CSNK1D,
CSPG4,
CTPS1,
CTSG,
CUX1,
CYP1A1,
CYP3A7,
CYP2B6,
CYP2C9,
DAP,
DCK,
DCN,
ACE,
NQO1,
DKC1,
DLX3,
DMD,
DNMT3A,
LRP4,
LRP6,
LRP5,
VHL,
WEE1,
XBP1,
XBP1P1,
YY1,
ZNF224,
BTG2,
BAG6,
DDX39B,
LAP,
FZD3,
NR4A3,
CUL5,
PTP4A2,
DPF3,
CDC7,
FZD4,
FZD6,
LOH19CR1,
RAD54L,
DENR,
KHSRP,
PSMG1,
PEA15,
ABCC3,
TNFRSF25,
RIPK1,
TNFSF14,
VWF,
VDAC1,
TNFRSF14,
UTRN,
TARBP2,
TARBP2P1,
TCF7,
TRB,
TRD,
TRGC1,
TF,
TFR2,
TGFA,
TGFBR1,
TIA1,
TIMP1,
TIMP2,
TJP1,
TLR1,
TSPAN7,
TMSB4X,
TNFRSF1B,
TNR,
HSP90B1,
TRAF1,
TRH,
TTK,
TUFM,
TNFSF4,
UCN,
USF1,
TNFSF9,
FADD,
ABCC8,
COX5A,
ATG5,
CLOCK,
AKAP12,
KDM4A,
DCAF1,
PIEZO1,
MTSS1,
MELK,
DDX46,
SLC23A2,
TNFSF15,
NR1H4,
HDAC6,
PDCD6,
ABCB6,
RNF41,
DDX39A,
KLRG1,
RASGRP2,
SPRY2,
CDK2AP2,
STUB1,
LILRB2,
TFG,
TUBB4B,
PIAS3,
PRMT5,
COG1,
SLC22A8,
TNFRSF18,
ADIPOQ,
TNFRSF10C,
TNFRSF10B,
IL18RAP,
IL18R1,
IQGAP1,
HDAC3,
PROM1,
MBD2,
HSPB3,
TNFSF18,
F2RL3,
HIP1R,
LATS1,
ARHGEF1,
CBFA2T2,
SLC28A1,
LPAR2,
IL1RL1,
ZMYM3,
AIMP1,
ITGB1BP1,
S1PR2,
TRIP13,
TRIP10,
CD163,
SLC22A6,
LONP1,
SUV39H1,
AURKA,
LSAMP,
NFKB2,
NGFR,
NOTCH3,
PNP,
NPAS2,
NPAT,
YBX1,
NTRK1,
ROR2,
NTS,
NUP98,
OCA2,
ODC1,
OSM,
PAEP,
PBX1,
PCYT1A,
PDE4B,
PDE4D,
PDE1B,
PECAM1,
PENK,
PGM3,
PHB,
PIGR,
PIK3C2B,
PIK3R1,
PLAGL1,
NGF,
NEUROD1,
PLXNA2,
NDUFAB1,
LTB,
MXD1,
MAD2L1,
SMAD2,
SMAD7,
MAGEA1,
MAS1,
MCC,
MCM7,
MEF2D,
MAP3K5,
MEN1,
CD99,
MIF,
CXCL9,
MAP3K11,
KMT2A,
MLLT1,
MNDA,
MPL,
MRC1,
MSH2,
COX2,
MYBL2,
MYCL,
MYT1,
NCL,
PLK1,
PLXNB1,
STIM1,
RPL11,
RPS27,
S100A8,
S100A9,
SALL1,
SAT1,
CCL2,
CCL11,
CCL13,
CCL22,
SDHB,
SGK1,
SI,
PMEL,
STIL,
SLC2A4,
SLC6A3,
SLC16A1,
SLC22A2,
SNRPN,
SOD2,
SPN,
SRC,
SRF,
NAT2,
SSTR4,
STAT4,
SULT1E1,
RPS19,
RPL10,
PML,
RPA1,
POU2F2,
PPARD,
PPARG,
PRCP,
PRELP,
PREP,
PRKD1,
MAPK8,
EIF2AK2,
PSMB6,
PTCH1,
PTN,
PTPN4,
RAC2,
RAD21,
RAD52,
RAG1,
RAP1A,
RARA,
RARS1,
PLAAT4,
RASGRF1,
RBP4,
OPN1LW,
RELB,
RENBP,
RET,
SSTR2
Drugs
4-ethoxy-2-(piperazin-1-yl)-7-(pyridin-4-yl)-5H-pyrimido[5,4-b]indol,
Acadesine,
Acalabrutinib
(
CALQUENCE
)
4-ethoxy-2-(piperazin-1-yl)-7-(pyridin-4-yl)-5H-pyrimido[5,4-b]indol,
Acadesine,
Acalabrutinib
(
CALQUENCE
),
Alemtuzumab
(
CAMPATH
),
Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpesvirus-6, Epstein Barr virus and adenovirus,
Alvocidib,
Autologous engineered anti -CD19 Chimeric Antigen Receptor (CAR +) T -cells
(
KYMRIAH
),
Autologous human peripheral blood Vdelta1+ T lymphocytes activated in vitro by cytokine and monoclonal antibody treatment,
Axicabtagene ciloleucel
(
YESCARTA
),
Bendamustine for 50 ml admixture
(
BENDEKA
),
Bruton's tyrosine kinase inhibitor,
Cenersen,
Cladribine
(
LITAK
),
Deoxyribose phosphorothioate (5´-tct-ccc-agc-gtg-cgc-cat-3´),
Dinaciclib,
Duvelisib
(
COPIKTRA
),
Entospletinib,
Forodesine,
Human monoclonal antibody against HLA-DR,
Humanised Fc engineered monoclonal antibody against CD19,
Humanised agonistic anti-CD28 monoclonal antibody,
Humanised single chain monoclonal antibody against CD37,
Ibrutinib
(
IMBRUVICA
),
Idelalisib
(
ZYDELIG
),
Inecalcitol,
Iodine (131I) tositumomab,
Lenalidomide
(
LENALIDOMIDE ACCORD,
REVLIMID
),
Lumiliximab,
Milatuzumab,
Obinutuzumab
(
GAZYVA,
GAZYVARO
),
Ofatumumab
(
ARZERRA
),
Recombinant anti-CD40 monoclonal antibody,
Recombinant antibody derivative against human CD19 and CD3,
Recombinant chimeric monoclonal antibody against CD20,
Rituximab
(
BLITZIMA,
MABTHERA,
TRUXIMA,
RITEMVIA,
RITUXAN,
RITUZENA,
RIXATHON,
RIXIMYO,
Ruxience
),
Spebrutinib,
Veltuzumab,
Venetoclax
(
VENCLEXTA,
VENCLYXTO
),
haematopoietic stem cells and blood progenitors umbilical cord-derived expanded with (1R, 4R)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine dihydrobromide dihydrate
Registered!
Chronic lymphocytic leukemia (CLL) is a type of cancer of the white blood cells (lymphocytes). Early signs and symptoms may include swollen lymph nodes, fatigue, weight loss, fever, night sweats and/or frequent infections. CLL usually occurs in adults around the age of 70 and begins in the bone marrow and then spreads to the blood. Over time, CLL may also spread to the lymph nodes and other organs, including the liver, spleen and lungs. The severity and outcome of CLL depends on many factors. The underlying cause is thought to be a combination of genetic and other unknown factors. It usually occurs in people with no family history of the condition, but familial cases have been reported. CLL is diagnosed based on the symptoms and various blood tests. Treatment options depend on many factors, including the stage of the condition, blood cell counts, and whether the CLL has recurred (come back).