Melanoma Of Soft Tissue

Watchlist

(log in to enable)

Retrieved

2021-01-23

Source

Orphanet

Trials

—

Genes

EWSR1, ATF1, CREB1, BCOR, CD6, MITF, BRAF, KIT, GDNF, MET, S100A1, S100B, ERBB3, IGF2, NRAS, MLANA, EGFR, CCS, CREM, CDKN2A, VIM, TYR, TFE3, SST, CIC, CRTC1, TRIM11, RTL1, PTEN, PLAU

EWSR1, ATF1, CREB1, BCOR, CD6, MITF, BRAF, KIT, GDNF, MET, S100A1, S100B, ERBB3, IGF2, NRAS, MLANA, EGFR, CCS, CREM, CDKN2A, VIM, TYR, TFE3, SST, CIC, CRTC1, TRIM11, RTL1, PTEN, PLAU, PDGFRB, P4HB, AOC1, NBN, MYC, CD151, CREBBP, CSF3, DDIT3, HBEGF, E2F4, FOS, FUS, MSH6, NRG1, IL6, CD99, MLH1, MRC1, MSH2, LINC01194

Drugs

—

Interested in hearing about new therapies?

A rare soft tissue tumor characterized by a slowly growing mass typically involving tendons and aponeuroses of the extremities, composed of polygonal or spindle-shaped cells with melanocytic differentiation. The tumor typically affects young adults, who often present with pain or tenderness at the tumor site. Prognosis is poor with high recurrence rates and frequent metastasis, especially to lymph nodes, lung, and bones.