Congenital Hemolytic Anemia

Congenital hemolytic anemia refers to hemolytic anemia which is primarily due to congenital disorders.

Types

Basically classified by causative mechanism, types of congenital hemolytic anemia include:

• Genetic conditions of RBC Membrane
  • Hereditary spherocytosis
  • Hereditary elliptocytosis
• Genetic conditions of RBC metabolism (enzyme defects). This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding hemoglobin abnormalities as well, but rather encompassing defects of glycolysis in the erythrocyte.
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD or favism)
  • Pyruvate kinase deficiency
  • Aldolase A deficiency
• Hemoglobinopathies/genetic conditions of hemoglobin
  • Sickle cell anemia
  • Congenital dyserythropoietic anemia

• • Thalassemia

See also

• Hematopoietic ulcer
• List of circulatory system conditions