Anotia Watchlist (log in to enable) Retrieved 2021-01-23 Source Orphanet Trials — Genes CDC6, CHUK, FANCB, HOXA2, ORC1, ORC4, CDC45, ORC6, POLR1A, GMNN, CDT1 Drugs — Interested in hearing about new therapies? Registered! A congenital malformation of the external ear and the most extreme form of microtia characterized by the complete absence of the external ear and auditory canal, conductive hearing loss, attention deficit disorders and delayed language development.