Eyebrows, Duplication Of, With Stretchable Skin And Syndactyly

Clinical Features

Berkenstadt et al. (1988) described partial duplication of the eyebrows with other anomalies in a 7-year-old son of parents related as half sibs. (They were called first cousins; however, they were the offspring of identical twins). The boy was of normal intelligence. There was excess hair on the forehead and long eyelashes as well as excessive wrinkling of the periorbital skin when the eyes were closed. He had bilateral syndactyly involving the second to the fourth fingers and the second and third toes. The skin was excessively stretchable on the face and chest. There was no joint hypermobility. Two brothers were normal.

Gross-Kieselstein and Har-Even (1989) described the same disorder in brother and sister of North African Jewish descent. The parents were unrelated and unaffected. The brother, a 6-year-old, had duplication of the eyebrows mainly in the lateral portions, congenital fibromata of the lips, and bilateral mild syndactyly involving the second to fourth fingers and second and third toes. There was no hyperelasticity of the skin or abnormal periorbital wrinkling. The sister, aged 11 years, showed, in addition to the other findings, hyperelasticity of the skin of the cheeks and marked hypermobility of the interphalangeal joints.