Lymphokine Deficiency
Chronic mucocutaneous candidiasis can have many causes, e.g., (1) failure of lymphocytes to transform in response to antigen, either because of an intrinsic defect (247450) or because of an inhibiting serum factor (247430); (2) failure of production of lymphokine; or (3) unresponsiveness of monocytes to lymphokine (252250). Deficient production of lymphokine despite normal lymphoblastic transformation was demonstrated by Lehner et al. (1972).