Intestinal Pseudoobstruction With Patent Ductus Arteriosus And Natal Teeth

Harris et al. (1976) described 2 male sibs with mandibular teeth present at birth, patent ductus arteriosus (see 607411), and intestinal pseudoobstruction evident from birth. Vomiting of bile stain material began soon after birth, and there was no passage of meconium. The older brother died at 5 months of age despite 2 gastrointestinal operations and ligation of the patent ductus arteriosus which had led to cardiac failure. The younger brother died at the age of 6 weeks. Either autosomal or X-linked recessive inheritance is possible.