Low-Set Ears
Watchlist
Retrieved
2021-01-18
Source
Trials
—
Genes
ARID1A,
IFT52,
PAM16,
MRPS16,
KCNK4,
EFEMP2,
DONSON,
PSAT1,
SLC25A24,
POMT2,
PYCR2,
ANKRD11,
IFT81,
DCPS,
CCDC22,
PCLO,
AHDC1,
GPKOW,
INTU,
FOXP1,
B9D1,
FGF20,
VPS33B,
B3GAT3,
KIFBP,
TCTN3,
AUTS2,
SETBP1,
C2CD3,
GMNN
ARID1A,
IFT52,
PAM16,
MRPS16,
KCNK4,
EFEMP2,
DONSON,
PSAT1,
SLC25A24,
POMT2,
PYCR2,
ANKRD11,
IFT81,
DCPS,
CCDC22,
PCLO,
AHDC1,
GPKOW,
INTU,
FOXP1,
B9D1,
FGF20,
VPS33B,
B3GAT3,
KIFBP,
TCTN3,
AUTS2,
SETBP1,
C2CD3,
GMNN,
ACOX1,
SAMHD1,
ZDHHC9,
OSGEP,
CHD7,
POMGNT1,
ACER3,
ASXL2,
SETD5,
PHIP,
PPP2R3C,
TMEM70,
MKS1,
BCOR,
QRICH1,
AHI1,
GTPBP2,
MAGEL2,
PUS7,
TMCO1,
WNT4,
RIPK4,
BCL11A,
RAB23,
OTUD6B,
DYNC2LI1,
PIGT,
LARP7,
MBTPS2,
TMEM216,
MMACHC,
NIPBL,
PACS1,
ORC6,
EBP,
STAMBP,
POMT1,
COLEC10,
RNASEH2A,
ZBTB18,
COG5,
PIBF1,
TUBB3,
RXYLT1,
KLHL41,
CWC27,
ZMPSTE24,
IRX5,
SF3B4,
CD96,
GPC6,
HUWE1,
GNE,
HDAC6,
SLC12A6,
MED12,
WASHC5,
FIG4,
RUSC2,
ZBTB24,
KIAA0586,
STAG2,
SEPTIN9,
MAPRE2,
KIAA0556,
PIGN,
ATP6V0A2,
KAT6B,
TGDS,
EXOSC2,
ADNP,
MED13L,
SPECC1L,
CLASP1,
RPGRIP1L,
SATB2,
CAMTA1,
MAPK8IP3,
B4GAT1,
POGZ,
TAB2,
SPART,
CNOT1,
DHX30,
CILK1,
CHSY1,
MRAS,
B4GALT7,
TREX1,
MAN1B1,
POLR3A,
PEX26,
FRMD4A,
TMEM94,
B3GLCT,
KLHL40,
DIS3L2,
SYT2,
TWIST2,
MYSM1,
C12orf57,
CEP41,
PGAP3,
MARS2,
COG7,
ATPAF2,
TMEM67,
HS6ST2,
RSPRY1,
UBE3B,
WDR73,
POMGNT2,
GPT2,
MYO18B,
TMEM107,
TRAF7,
POMK,
ANTXR1,
KIAA1109,
RNASEH2C,
CDCA7,
ITCH,
AMER1,
CCBE1,
VAC14,
B3GALNT2,
OCLN,
RNU4ATAC,
CRPPA,
AGRN,
KIF7,
CTU2,
RSPO2,
SH3PXD2B,
UNC80,
KCTD1,
CHAMP1,
NALCN,
PTF1A,
EBF3,
STAC3,
PHACTR1,
JMJD1C,
HYLS1,
TUBB,
TAPT1,
ARL13B,
ASXL1,
ARX,
GLIS3,
BMPER,
ESCO2,
CEP120,
PLVAP,
CDT1,
ARMC9,
FBXO11,
VIPAS39,
ALX4,
SLC5A7,
EPG5,
DOCK6,
CC2D2A,
WDR35,
ARID1B,
PRR12,
TBC1D24,
GATAD2B,
ADGRG6,
KIF15,
FAM20C,
MRPS22,
INPP5E,
LRRC8A,
LMOD3,
SMG9,
KLHL7,
ZC4H2,
TMEM165,
CENPJ,
LMBRD1,
MCTP2,
MBD5,
TENM3,
PIEZO2,
MRPS14,
SMOC1,
TCTN1,
FRAS1,
GREB1L,
ALG13,
TCTN2,
CSPP1,
EHMT1,
ALG9,
TXNDC15,
SRD5A3,
FAT4,
EFL1,
RNASEH2B,
TMEM231,
SLC39A8,
FKRP,
ALG8,
COLEC11,
CPLANE1,
UPF3B,
TMEM237,
PORCN,
NXN,
NSD1,
STRA6,
IFIH1,
XYLT2,
EIF4A3,
CEP104,
ACP5,
MEGF8,
GP1BB,
GNS,
GNAI3,
GLUL,
GLE1,
GK,
GJB2,
GJA1,
GDNF,
GBA,
GATA4,
FZD2,
MTOR,
FLNB,
FLNA,
FHL1,
FGFR2,
FGFR3,
FGFR1,
GPC4,
FKTN,
FBN1,
FANCB,
EYA1,
EVC,
ERCC5,
ERCC4,
BRF1,
H3-3A,
HELLS,
LMNA,
MYCN,
MVK,
ATP6,
KMT2A,
MEIS2,
MEF2C,
MECP2,
MCM5,
MAF,
SMAD4,
MAB21L1,
LRP2,
LIFR,
HNRNPK,
LBR,
KRAS,
KIF22,
KCNJ2,
IREB2,
INSR,
IGF2,
IGF1R,
IGBP1,
HSPG2,
HSD17B4,
HRAS,
EP300,
EEF1A2,
MYO9A,
EDNRA,
CHD3,
CHAT,
CENPF,
CDKN1C,
CDH11,
CDC42,
CDC6,
CBL,
CAMK2G,
BUB1B,
BRAF,
BMPR1A,
BMP2,
ATRX,
ATR,
ATP6V1E1,
ATP6V1A,
ATIC,
ASCL1,
ARVCF,
ARL3,
ALX3,
AKT1,
ADSL,
ADAR,
ACTB,
ACTA1,
CHD4,
CHRNA1,
CHRND,
DDX3X,
EDN3,
DVL3,
DVL1,
SLC26A2,
ATN1,
DPH1,
DNMT3B,
DLX4,
DHPS,
DHODH,
DHCR24,
DHCR7,
DAG1,
CHRNG,
CTSD,
CTNNB1,
CSNK2A1,
CRMP1,
CREBBP,
CPT2,
COMT,
COL13A1,
COL11A2,
COL11A1,
COL4A1,
COL2A1,
MYH3,
NEB,
CEP57,
SOX4,
USP9X,
LZTR1,
SHOC2,
KAT6A,
PCGF2,
YWHAE,
WNT7A,
WNT5A,
WNT3,
VARS1,
UFD1,
TWIST1,
HIRA,
TPM3,
TPM2,
TFAP2B,
TFAP2A,
TCF20,
TBX15,
TBX2,
TBCE,
TBX1,
TALDO1,
TAF1,
VAMP1,
SOX11,
SOX9,
RBM10,
SMC1A,
NAA10,
PHOX2B,
PUM1,
TTC37,
SEC24C,
ADAMTS3,
CHST3,
PLAA,
EFTUD2,
CRLF1,
LARGE1,
PLOD3,
AP3D1,
KYNU,
HERC1,
TRRAP,
CCNK,
EED,
CDK13,
CDK10,
AP3B1,
ITGA8,
CNTNAP1,
PEX3,
PPM1D,
OFD1,
PLA2G6,
CDC45,
SOX5,
SON,
NF1,
SNRPB,
PSMD12,
MASP1,
PRPS1,
PPP2R1A,
PPP1CB,
POR,
POLE,
EXOSC9,
PMM2,
PLCB4,
PEX12,
PEX10,
PCNT,
PBX1,
PAX1,
PRDX1,
PAFAH1B1,
OTX2,
ORC4,
ORC1,
NUP88,
NRAS,
NPR2,
NOTCH3,
NOTCH2,
NFIX,
NFIA,
PTCH1,
PTEN,
PTH1R,
RPS23,
SNAP25,
SMS,
SMARCD2,
SLC25A1,
SLC18A3,
SLC6A9,
SLC6A8,
SKI,
SIM1,
SCN4A,
SCN1A,
RREB1,
RPS6KA3,
PTPN11,
RPL35A,
RIT1,
RET,
DPF2,
RB1,
RARB,
RAF1,
RAC1,
QARS1,
ALDH18A1,
PEX5,
PEX2,
SCN1A-AS1
Drugs
—
Registered!
Clinical sign of congenital conditions
Low-set ears are a clinical feature in which the ears are positioned lower on the head than usual. They are present in many congenital conditions. Specifically, low-set ears are defined as outer ears positioned two or more standard deviations lower than the population average.
Low-set ears can be associated with conditions such as:
- Down syndrome
- Turner syndrome
- Noonan syndrome
- Patau syndrome
- DiGeorge syndrome
- Cri du chat syndrome
- Edwards syndrome
- Fragile X syndrome
- Okamoto syndrome
It is usually bilateral, but it can be unilateral in Goldenhar syndrome.
See also
- LEOPARD syndrome