African Iron Overload Watchlist (log in to enable) Retrieved 2021-01-23 Source Orphanet Trials — Genes — Drugs (S)-3'-(OH)-desazadesferrithiocin-polyether, magnesium salt Interested in hearing about new therapies? Registered! A rare disorder described in sub-Saharan African populations and characterized by iron overload due to excess dietary iron intake and possibly genetic factors, leading to hepatic portal fibrosis and micronodular cirrhosis.