Hemolytic Uremic Syndrome

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Retrieved

2022-04-26

Source

Gard

Trials

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Genes

CD46, DGKE, C3, CFB, CFH, IL6, IL1B, TNF, NQO1, ALB, IL1A, EPO, CCL2, ADAMTS13, CFI, CFHR1, THBD, CFHR3, MMACHC, PRDX1, STX1A, TRIM25, STX2, VWF, CAPG, RNR2, ST8SIA2, IL10, PCSK5, PLG

CD46, DGKE, C3, CFB, CFH, IL6, IL1B, TNF, NQO1, ALB, IL1A, EPO, CCL2, ADAMTS13, CFI, CFHR1, THBD, CFHR3, MMACHC, PRDX1, STX1A, TRIM25, STX2, VWF, CAPG, RNR2, ST8SIA2, IL10, PCSK5, PLG, SH3BP4, MTHFR, CXCR4, F3, MCHR2, CXCL12, ZFP36, TLR4, CCR2, LIPG, PLA2G7, ST11, MIR126, GRHPR, WT1, AIMP2, ACKR3, GADL1, SUMF2, A4GALT, CLEC1B, DBR1, DESI1, HPLH1, CFHR5, POLDIP2, RNF19A, IL33, GRAP2, CADM1, NT5C2, AZIN2, SLC35G1, IL24, RAB7B, NLE1, AHSA1, ABO, SAA2, TP53, FGF2, EDN1, SLC25A10, MAPK14, CRK, CPB2, CLU, CDA, CD40LG, CD22, CAT, CASP1, VPS51, C4BPA, C3AR1, APCS, ANGPT2, ANGPT1, FABP1, FHL1, TM7SF2, HLA-DRB1, TGFB1, SPARC, CX3CL1, CCL20, CCL4, AGT, SAA1, REN, MAPK1, COX1, MATK, IL18, CXCL8, IL4R, IL2RA, IFNB1, HMGB1, RN7SL263P

Drugs

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Hemolytic uremic syndrome (HUS) is a disorder that usually occurs when an E. coli bacterial infection in the digestive system produces toxic substances that destroy red blood cells. Symptoms include vomiting and diarrhea, fever, lethargy, and weakness. In severe cases it can lead to kidney failure or death. While this condition is most common in children, it often has a more complicated presentation in adults. Treatment may include dialysis, corticosteroids, transfusions of packed red blood cells and plasmapheresis.

Hemolytic uremic syndrome should be distinguished from syndrome/resources/1" target="_blank">atypical hemolytic uremic syndrome (aHUS). The two conditions have different causes and different signs and symptoms.