Neutropenia, Lethal Congenital, With Eosinophilia

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Retrieved

2019-09-22

Source

Omim

Trials

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Genes

ELANE, TCIRG1, GFI1, SRP54

Drugs

Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpesvirus-6, Epstein Barr virus and adenovirus, haematopoietic stem cells and blood progenitors umbilical cord-derived expanded with (1R, 4R)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine dihydrobromide dihydrate

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Andrews et al. (1960) described 2 affected sibs. The parents were not known to be related. It is not entirely certain that this is an entity separate from that listed as agranulocytosis (202700). It is possible that some cases of neonatal neutropenia are due to fetomaternal immunization involving neutrophil-specific antigens (Lalezari and Radel, 1974).