Galactorrhea

Wider et al. (1969) described 3 sisters with nonpuerperal galactorrhea occurring after treatment with oral contraceptive. Although all 3 had oligoovulation, the evidence suggested independent control of ovulation and lactation: galactorrhea continued in one sister while she took an oral contraceptive containing estrogen-progesterone, which presumably suppressed production of plasma gonadotropin. Galactorrhea continued even when ovulation was induced by measures which stimulated the release of gonadotropins. Two of the sisters conceived after ovulations which occurred despite continuing galactorrhea.