Central Serous Chorioretinopathy

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Retrieved

2022-04-26

Source

Gard

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Genes

NR3C2, CD44, PROM1, PLXNA2, ALDH1A1, CTNNB1, SOX2, CD24, FOXM1, EGFR, ERBB2, POU5F1, POU5F1P3, POU5F1P4, BECN1, VEGFA, NOTCH1, TNF, CFH, DNMT1, STAT3, HES1, SLC22A3, DYNC2H1, HDAC2, MAPK1, IL6, YAP1, PLG, NFATC3, OSM, SERPINE1, PIK3CA, PIK3CB, PIK3CD, PIK3CG, AKT1, ALCAM, TP53, ZEB1, JAG1, LGR5, MIR145, MIR146A, MIR200C, NRP1, NMU, KAT7, STRAP, H4C8, H4C9, H4C3, RAD51AP1, H4C11, H4C12, H4C6, H4C4, H4C1, NES, H4C2, AHSA1, ATG7, TRAP1, ABCB6, TBPL1, ABCG2, GRAP2, KLF4, DCLK1, H4C5, OSMR, H4C13, H4C14, CLDN2, MBD2, ADM, KLF12, MIR155, CD109, RMDN2, SHISA3, DNAJB8, DNAJB1P1, ARMS2, MIR10B, MIR137, MIR150, MIR200B, CBX5, MIR203A, MIR21, MIR219A1, MIR23B, MIR31, MIR95, H4C15, MIR874, GATD3B, H4-16, ORAI1, FSD1L, AGBL2, CBX7, RNF19A, POLDIP2, SLC7A5, FBXO8, RMDN1, HDAC7, PINX1, RMDN3, FBXW7, SYBU, PAG1, KIF15, ACKR3, PCBP4, SPC25, WDR48, FBRS, FSD1, GATD3A, PRDX2, ADAM12, AIMP2, EIF4E, EZH2, F3, PTK2B, FGF5, FN1, GLI1, GSK3B, GSTM1, HDAC1, HMGB1, HOXB3, HSF1, HSPA4, DNAJB1, IFNB1, CXCL8, ITK, KIT, EGR3, DUSP5, DNMT3A, CAV1, AKT2, APC, AR, BAX, BMI1, BMP2, BMP7, BNIP3L, RUNX3, DDX3X, CDH5, CDK2, CREBBP, CRK, CRP, MAPK14, CSF2, DAB2, LAMC2, LGALS1, LOX, TGFB1, SMN2, SOX9, SOX15, SRF, AURKA, ADAM17, TEAD1, TERF2, TGM2, SLC16A1, TLR3, TRAF6, TWIST1, EZR, VIM, WIPF1, PCGF2, CXCR4, SMN1, SLC12A3, EPCAM, MAPK9, SMAD2, MMP11, COX2, NELL1, PECAM1, PLAT, MAPK3, MAPK8, MAP2K7, SLC3A2, PTEN, PTGS2, PTPRB, RAC1, OPN1LW, REN, SDC1, CXCL12, MTCO2P12

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Central serous chorioretinopathy (CSCR) occurs when fluid builds up under the retina, the back part of the inner eye that sends sight information to the brain. The fluid leaks from the choroid (the blood vessel layer under the retina), and can lead to retinal detachment. Signs and symptoms include dim and blurred vision, a blind spot in the center of vision, distortion of straight lines, and seeing objects as smaller or farther away. The cause of this condition is unknown, but it is thought to be due to a combination of genetic and environmental factors. Risk factors include steroid use, stress, certain infections, and sleep disorders. In rare cases, CSCR can occur in several members of the same family. Diagnosis of CSCR is based on different imaging techniques. Treatment is focused on improving vision and preventing future occurrences. Many cases of central serous chorioretinopathy improve without treatment after 1-2 months. Laser treatment, light treatments, and medications may be an option for other individuals.