Syndactyly-Polydactyly-Earlobe Syndrome
Clinical Features
Goldberg and Pashayan (1976) reported 10 members over 3 generations of a family with a syndrome involving syndactyly, polydactyly, and earlobe malformations. The syndactyly was an unusual complete cutaneous type involving toes 1 and 2. Ulnar polydactyly varied from postminimi nubbins to nearly complete sixth finger. The earlobes showed either a deep horizontal groove or a nodule. The feet also showed a broad or bifid great toe or in some a complete, separate, preaxial extra toe.
InheritanceGoldberg and Pashayan (1976) stated that the pedigree pattern in the family they reported was compatible with autosomal dominant inheritance because there were 2 instances of male-to-male transmission.