Hemicrania Continua

Hemicrania continua is a rare, indomethacin-responsive, trigeminal autonomic cephalgia characterized by a typically side-locked, continuous, unilateral headache of moderate intensity with recurrent episodes of exacerbations of severe intensity, lasting for more than 3 months, in the absence of structural brain or vascular lesions. Ipsilateral cranial autonomic symptoms (lacrimation, conjunctival injection, nasal congestion or rhinorrhea, ptosis/miosis), restlessness and/or migrainous features are observed during the exacerbations.