Microstomia
Watchlist
Retrieved
2021-01-18
Source
Trials
—
Genes
ABL1,
MAPRE2,
AKT3,
HUWE1,
PQBP1,
ZMPSTE24,
SPEG,
SEPTIN9,
SRCAP,
TXNL4A,
TLK2,
PIGN,
POLR3A,
B4GALT7,
CHSY1,
POGZ,
MAPK8IP3,
CAMTA1,
SATB2,
CLCF1,
MED12,
AMMECR1,
EIF4A3,
SEMA3E,
ZBTB16,
BRPF1,
CDC45,
KCNAB2,
CDK13,
TP63
ABL1,
MAPRE2,
AKT3,
HUWE1,
PQBP1,
ZMPSTE24,
SPEG,
SEPTIN9,
SRCAP,
TXNL4A,
TLK2,
PIGN,
POLR3A,
B4GALT7,
CHSY1,
POGZ,
MAPK8IP3,
CAMTA1,
SATB2,
CLCF1,
MED12,
AMMECR1,
EIF4A3,
SEMA3E,
ZBTB16,
BRPF1,
CDC45,
KCNAB2,
CDK13,
TP63,
DCHS1,
CRLF1,
TRIP4,
COG1,
RECQL4,
CHST3,
TBX4,
ADAMTS3,
POLR1C,
SEC24C,
TTC37,
ATP6V0A2,
ORC6,
AKT1,
SP7,
PRDM16,
BCL11B,
FAT4,
FBXO11,
CDT1,
UBE3B,
COG7,
CHST14,
CANT1,
RTTN,
TBC1D20,
GSC,
CCBE1,
TUBB,
JMJD1C,
PHACTR1,
NALCN,
RSPO2,
PIEZO2,
TRMT5,
GATAD2B,
FAM20C,
SIN3A,
SH2B1,
AUTS2,
ZBTB20,
B3GAT3,
DCPS,
DSE,
SLC25A24,
DONSON,
GMNN,
POLR1D,
RLIM,
RIPK4,
IMPAD1,
CHD7,
OSGEP,
IARS2,
PCGF2,
YWHAE,
WNT3,
GP1BB,
BPTF,
FBN1,
FGFR2,
FLNA,
GABRD,
GBA,
GJA1,
GNAI3,
HIVEP2,
UFD1,
HSPG2,
IGF1R,
ITGA3,
LAMA3,
LAMB3,
LAMC2,
LMNA,
LTBP3,
EP300,
EDN1,
DHCR24,
CRKL,
BIN1,
APC,
ARVCF,
RERE,
BCR,
BMP2,
BMPR1A,
CCND2,
CDC6,
CHRNG,
COL2A1,
COL3A1,
COL7A1,
COL11A1,
COL11A2,
COMT,
CREBBP,
SMAD4,
MAF,
MCM5,
TAF6,
PTEN,
ALDH18A1,
RPL10,
RREB1,
RYR1,
SKI,
SMS,
SON,
TBX1,
MAPK1,
TCOF1,
TNNI2,
TNNT3,
TPM2,
TTN,
TTPA,
HIRA,
TWIST1,
PTCH1,
POLD1,
MECP2,
ORC1,
MMP1,
MUSK,
MYBPC1,
MYH3,
NFIA,
NFIX,
NONO,
NOTCH2,
ORC4,
PRRX1,
OTX2,
PAFAH1B1,
PAX3,
PIGA,
PIK3CA,
PIK3R2,
PLCB4,
FREM2,
BARX1
Drugs
—
Registered!
Abnormally small mouth
Microstomia is a small mouth (micro- a combining form meaning small + -stomia a combining form meaning mouth = (abnormally) "small mouth" in Greek.)
Congenital
It is a feature of many craniofacial syndromes, including Freeman–Sheldon syndrome and Sheldon-Hall syndromes (or distal arthrogryposis multiplex congenita). It may present with whistling-face feature, as well, as in Freeman-Sheldon syndrome. In this syndrome, it impairs alimentation and may require repeated oral surgeries (called commissurotomy) to improve function.
Acquired
Microstomia can occur as a result of scarring due to many conditions. It is seen as complication of facial burns. It can also be a feature of systemic scleroderma.