Heart, Malformation Of
Watchlist
Retrieved
2019-09-22
Source
Trials
—
Genes
JAG1,
GDF1,
ZEB2,
MAML3,
MTHFR,
TBX1,
VEGFA,
ABCB1,
HAND2,
RCAN1,
MYH6,
AHR,
POU5F1,
HIF1A,
AFF4,
TGFB2,
ABL1,
NPPB,
STRA6,
PITX2,
EDN1,
HOXA3,
KLF4,
GP1BB,
GNAQ,
TRRAP,
ECE1,
GNA11,
EDNRA,
UFD1
JAG1,
GDF1,
ZEB2,
MAML3,
MTHFR,
TBX1,
VEGFA,
ABCB1,
HAND2,
RCAN1,
MYH6,
AHR,
POU5F1,
HIF1A,
AFF4,
TGFB2,
ABL1,
NPPB,
STRA6,
PITX2,
EDN1,
HOXA3,
KLF4,
GP1BB,
GNAQ,
TRRAP,
ECE1,
GNA11,
EDNRA,
UFD1,
THAS,
MEIS2,
EYA1,
GATA4,
FOLR1,
TMEM94,
HOXA1,
BRD4,
IRX5,
TRAF7,
SLC29A3,
CBFB,
CAV3,
STAG2,
NIPBL,
NKX2-5,
DNMT3A,
SAP130,
DNMT3B,
RXRA,
DNMT1,
TCOF1,
SOX9,
SMARCA4,
ARID1A,
FGFR2,
RAI1,
PEX5,
HYMAI,
PEX2,
KIF7,
INS,
PDX1,
PIGV,
ZFP57,
PLAGL1,
LMBR1,
MID1,
CPLANE1,
PDE6D,
KCNJ11,
FAT4,
ALG9,
FAM149B1,
COG7,
FRAS1,
MED12,
RAD51C,
SAA1,
EBP,
CERS1,
EIF2AK3,
RECQL4,
SLC7A7,
DCHS1,
OFD1,
CIT,
POGZ,
SETBP1,
TWIST1,
TCTN3,
SLC25A24,
TBX5,
TMEM216,
LRP1B,
ABCC8,
KIAA0753,
SMARCB1,
STAT3,
STX18-AS1,
FANCA,
FANCC,
GCK,
GATA3,
COL3A1,
CHRM3,
GLI3,
FANCE,
FANCD2,
PTPN11,
GATA6,
CHD7,
GJA1,
CHDH,
TAB2,
ZIC3,
DGCR,
NR2F2,
MED13L,
CITED2,
G6PC3,
CRKL,
HTC2,
ALDH2,
CREBBP,
CRELD1,
APOE,
FOXC1,
TBX20,
HEY2,
RAF1,
COL6A1,
DSP,
MKKS,
NOS3,
ELN,
NOTCH1,
SOX11,
ACTB,
ACVR1,
MTRR,
MTHFD1,
MTR,
SMN2,
DGCR8,
ACTC1,
CDK13,
ARSD,
DSCAM,
MEF2C,
CBS,
JARID2,
RIT1,
SSPN,
RERE,
SOX4,
TDGF1,
MYH7,
NFATC1,
DGCR2,
TEK,
TBX2,
HCN4,
BMPR1A,
HAND1,
PDLIM1,
VWF,
ACTA2,
COL6A2,
ADA2,
FOXP1,
ANKRD11,
NEK8,
KCNE5,
GNMT,
CCNH,
CDH5,
RRDX,
HPGDS,
CACNA1C,
B3GAT3,
BTF3P11,
KANSL1,
ANKRD1,
REM1,
SETD2,
PRDM6,
SH3PXD2B,
PPARGC1A,
AOS,
POTEF,
CPA1,
KATNB1,
MIR320A,
MIR10B,
MTHFS,
CELF2,
MIR10A,
NANOGP1,
CCR6,
ADAMTS13,
ZFPM2,
PUF60,
ZHX2,
DAAM1,
NCOA6,
CECR,
ZC3H12D,
TBC1D9,
MGRN1,
SNX8,
DICER1,
SIRT1,
RPGRIP1L,
OTUD6B,
BRAF,
APLNR,
PCBP4,
SALL4,
MIB1,
SENP2,
FASLG,
FBLN7,
TMEM135,
APOA1,
FKRP,
FSD1,
AIRE,
AAGAB,
AGRP,
SLC2A14,
NAA15,
CCDC151,
MED25,
SOX7,
JAM3,
FSD1L,
PPP1R1B,
GRK2,
TMEM87B,
MYLK3,
ADAR,
SMYD4,
MIB2,
MRPS22,
NTM,
PBRM1,
SAR1B,
CRIM1,
KLF13,
CCDC114,
NPHP4,
SEMA3D,
BHMT,
RIPPLY3,
KLHL24,
ZNF778,
BCOR,
ARGLU1,
SETD5,
SMG9,
QRSL1,
ATP2B2,
MED13,
LRRC59,
ATP2A2,
SHFM5,
ADAP2,
PAG1,
CENPJ,
MESP1,
SLC50A1,
PKD1L1,
REC8,
HNRNPA1,
CPB1,
TNFRSF11B,
PAPPA,
PBX3,
PDE2A,
PIK3CA,
PIK3CB,
PIK3CD,
PIK3CG,
PKD1,
PKD2,
PKHD1,
GAB1,
SERPINF2,
PLN,
PMP22,
FXN,
MAPK1,
MAPK3,
PROX1,
PTH,
PTGS2,
PTPN1,
FLT4,
RAC1,
FGFR1,
OPN1LW,
REN,
RFC1,
RLF,
ROCK1,
PAH,
OPCML,
RYR2,
OPA1,
GSTP1,
HOXA13,
IRF8,
IFNAR1,
IGF1,
IGF1R,
GRIN2A,
GRK5,
ISL1,
KCNJ6,
GNG5,
LMNA,
LOXL2,
LRP2,
LRPAP1,
SMAD2,
SMAD4,
MGST1,
GLB1,
MSX1,
MSX2,
GJA5,
NHS,
NNMT,
NODAL,
NONO,
NPPA,
GFAP,
NTRK3,
FGF10,
FEN1,
FGF19,
EGFR,
TRPV1,
WNT11,
SEM1,
FGF23,
KMT2D,
FXR1,
USP9X,
PHC1,
DYSF,
TNFSF11,
DNTT,
HYAL2,
TNFRSF11A,
TNFRSF10D,
GTF2H3,
BANF1,
APLN,
FOXH1,
BAZ1B,
ARTN,
TRDMT1,
ASH2L,
TBX18,
DNAH8,
MED23,
ACE,
CST3,
RGS6,
CPS1,
MEGF8,
UBE2A,
SCN1A,
EIF4E,
SCN5A,
SH3BGR,
SHMT1,
SLC2A3,
SLC6A4,
SLIT3,
SLN,
SMARCD3,
SMARCE1,
SOD1,
SOS1,
SOX12,
FABP3,
SUV39H1,
TAF1,
MAP3K7,
F3,
EPO,
TBX3,
ENO1,
NR2F1,
EMD,
TGFBR1,
TGFBR2,
TLR4,
TNF,
TNXB,
TPM1,
TSHR,
TNFRSF10C
Drugs
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Registered!
Nora et al. (1970) concluded that the frequency of congenital heart malformations in first-degree relatives of probands is close to the square root of the population frequency that Edwards (1960) suggested should be the case for a multifactorial disorder. Zetterqvist (1971) reported a family with many cases of various cardiac malformations.